KLRG1 Antikörper (Biotin)

Produktnummer ABIN371097

Produktdetails anti-KLRG1 Antikörper (Biotin)

Target: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Reaktivität: Maus

Wirt: Hamster

Klonalität: Monoklonal

Konjugat: Dieser KLRG1 Antikörper ist konjugiert mit Biotin

Applikation: Flow Cytometry (FACS)

Spezifität: This antibody reacts with Killer Cell Lectin-like Receptor G1 (KLRG1 formerly known as mouse MAFA or 2F1-Ag). It stains 30-60 % of NK1.1+CD3- splenocytes, and a small fraction of T cells in all mouse strains tested (C57BL/6, BALB/c, 129/J, C3H.SW, AKR/J, SJL). (Ref.1,5)

Produktmerkmale: Synonyms: KLRG1, CLEC15A, MAFA, MAFAL, Mast cell function-associated antigen, MAFA-like receptor,ITIM-containing receptor MAFA-L, Killer cell lectin-like receptor subfamily G member 1,C-type lectin domain family 15 member A

Immunogen: Activated NK (A-LAK) cells from B6 (H-2b) mice. (Ref. 1)

Klon: 2F1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Flow Cytometry: < / = 1 μg/10^6 cells. (Ref.1,5)
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: PBS containing 0.09 % Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or in (aliquots) at -20 °C for longer. This product is photosensitive and should be protected from light. Avoid repeated freezing and thawing.
Shelf life: one year from despatch.

Haltbarkeit: 12 months

Details zu KLRG1

Target: KLRG1 (Killer Cell Lectin-Like Receptor Subfamily G, Member 1 (KLRG1))

Andere Bezeichnung: KLRG1 (KLRG1 Produkte)

Synonyme: KLRG1 antikoerper, 2F1-Ag antikoerper, MAFA antikoerper, MAFA-L antikoerper, 2F1 antikoerper, CLEC15A antikoerper, MAFA-2F1 antikoerper, MAFA-LIKE antikoerper, killer cell lectin like receptor G1 antikoerper, killer cell lectin-like receptor subfamily G, member 1 antikoerper, KLRG1 antikoerper, Klrg1 antikoerper

Hintergrund: Killer cell lectin-like receptor G1 (KLRG1, formerly known as mouse MAFA or 2F1 Ag), a homodimeric member of the lectin-like type 2 transmembrane receptor family that contain characteristic immunoreceptor tyrosine-based inhibitory motifs (ITIMs) in their cytoplasmic domains. (Ref.1,2) These ITIMs interact with the SH2 domains of protein phosphatases such as SHP1. (Ref.3,4) Cell surface expression of KLRG1 is up-regulated by expression of MHC class I molecules. The effect of MHC class I expression is indirect, and can be mediated by interactions with class I-specific Ly49 inhibitory receptors. (Ref.1)Synonyms: C-type lectin domain family 15 member A, CLEC15A, ITIM-containing receptor MAFA-L, KLRG1, Killer cell lectin-like receptor subfamily G member 1, MAFA, MAFA-like receptor, MAFAL, Mast cell function-associated antigen

Gen-ID: 50928

UniProt: O88713