CAMK2G Antikörper (Calcium/calmodulin-Dependent Protein Kinase II gamma) (AA 284-288)

Details for Product anti-CAMK2G Antibody No. ABIN362984, Anbieter: Anmelden zum Anzeigen
Antigen
  • CAMK
  • CAMK-II
  • CAMKG
  • 5930429P18Rik
  • Camkg
  • calcium/calmodulin dependent protein kinase II gamma
  • calcium/calmodulin-dependent protein kinase II gamma
  • CAMK2G
  • Camk2g
Epitop
AA 284-288
15
12
12
9
6
6
6
5
5
3
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Human, Maus, Ratte (Rattus)
175
138
136
40
10
4
4
3
3
2
2
1
1
1
Wirt
Kaninchen
98
91
Klonalität
Polyklonal
Konjugat
Dieser CAMK2G Antikörper ist unkonjugiert
11
10
6
6
6
6
4
4
4
4
4
4
4
4
4
4
4
Applikation
Immunofluorescence (IF), Western Blotting (WB)
185
126
117
89
63
42
41
37
8
8
7
4
1
1
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Peptide sequence around AA 284-288 (Q-E-T-V-D) derived from Human CaMKII. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Isotyp IgG
Spezifität The antibody detects endogenous level of total CaMKII protein.
Reinigung The antibody was affinity-purified from rabbit antiserum by affinity-chromatography usingepitope-specific immunogen.
Plasmids, Primers & others Plasmide, Primers & weitere CAMK2G products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung CaMKII (CAMK2G Antibody Abstract)
Hintergrund CaM-kinase II (CAMK2) is a prominent kinase in the central nervous system that may function in long-term potentiation and neurotransmitter release. Member of the NMDAR signaling complex in excitatory synapses it may regulate NMDAR-dependent potentiation of the AMPAR and synaptic plasticity J Bossuyt, K Helmstadter, X Wu, et al. (2008) Ca2+/Calmodulin-Dependent Protein Kinase II {delta} and Protein Kinase D Overexpression Reinforce - Circulation Research, 102(6):695-702.
Molekulargewicht 50 kDa
NCBI Accession NP_150284
UniProt P11798
Pathways WNT Signalweg, Interferon-gamma Pathway, Hormone Transport, Myometrial Relaxation and Contraction, Regulation of long-term Neuronal Synaptic Plasticity
Applikations-hinweise Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Produkt verwendet in: Bossuyt, Helmstadter, Wu, Clements-Jewery, Haworth, Avkiran, Martin, Pogwizd, Bers: "Ca2+/calmodulin-dependent protein kinase IIdelta and protein kinase D overexpression reinforce the histone deacetylase 5 redistribution in heart failure." in: Circulation research, Vol. 102, Issue 6, pp. 695-702, 2008 (PubMed).

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