mGluR2/3 Antikörper (C-Term)

Produktnummer ABIN361454

Produktdetails anti-mGluR2/3 Antikörper

Target: mGluR2/3 (GRIA2/3) (Glutamate Receptor, Ionotropic, AMPA 2/3 (GRIA2/3))

Bindungsspezifität: C-Term

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser mGluR2/3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Specific for the ~100k GluR2/3 protein.

Kreuzreaktivität: Ratte (Rattus)

Homologie: chicken, human, mouse, zebra fish

Aufreinigung: Antigen Affinity Purified from Pooled Serum

Immunogen: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH

Anwendungsinformationen

Applikationshinweise: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Lagerung: -20 °C

Details zu mGluR2/3

Target: mGluR2/3 (GRIA2/3) (Glutamate Receptor, Ionotropic, AMPA 2/3 (GRIA2/3))

Andere Bezeichnung: GRIA2/3 (GRIA2/3 Produkte)

Synonyme: glutamate ionotropic receptor AMPA type subunit 2 antikoerper, GRIA2 antikoerper

Hintergrund: The ion channels activated by glutamate are typically divided into two classes. Those that are sensitive to N-methyl-D-aspartate (NMDA) are designated NMDA receptors (NMDAR) while those activated by (-amino-3-hydroxy-5-methyl-4-isoxalone propionic acid (AMPA) are known as AMPA receptors (AMPAR). The AMPAR are comprised of four distinct glutamate receptor subunits designated (GluR1-4) and they play key roles in virtually all excitatory neurotransmission in the brain (Keinänen et al., 1990,Hollmann and Heinemann, 1994). The GluR2 subunit is widely expressed throughout the nervous system where it is thought to play key roles in synaptic plasticity and learning and memory (Duprat et al., 2003,Seidenman et al., 2003,Chung et al., 2003,Yan et al., 2002). Anti-GluR2/3 Western blot of rat hippocampal lysate showing specific immunolabeling of the ~100k GluR2/3 protein.

Molekulargewicht: '100 kDa

Gen-ID: 29627

UniProt: P19491