SLC6A3 Antikörper (C-Term)

Produktnummer ABIN361429

Produktdetails anti-SLC6A3 Antikörper

Target: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC6A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: Specific for the ~88k DAT protein in Western blots. Cross-reaction with rat observed.

Kreuzreaktivität: Human, Maus, Non-Human Primate

Aufreinigung: Antigen Affinity Purified from Pooled Serum

Immunogen: Synthetic peptide corresponding to amino acid residues from the intracellular C-terminal region conjugated to KLH

Anwendungsinformationen

Applikationshinweise: Recommended Dilution: WB: 1:1000 IHC: (frozen sections, formaldehyde fixed tissue, unpublished observations): 1:1000 Quality Control: Western blots performed on each lot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Lagerung: -20 °C

Details zu SLC6A3

Target: SLC6A3 (Solute Carrier Family 6 (Neurotransmitter Transporter, Dopamine), Member 3 (SLC6A3))

Andere Bezeichnung: SLC6A3 (SLC6A3 Produkte)

Synonyme: DAT antikoerper, SLC6A3 antikoerper, Dat1 antikoerper, DAT1 antikoerper, PKDYS antikoerper, solute carrier family 6 member 3 antikoerper, solute carrier family 6 (neurotransmitter transporter), member 3 antikoerper, Sodium-dependent dopamine transporter antikoerper, solute carrier family 6 (neurotransmitter transporter, dopamine), member 3 antikoerper, SLC6A3 antikoerper, slc6a3 antikoerper, dat-1 antikoerper, Slc6a3 antikoerper

Hintergrund: The dopamine transporter (DAT) is responsible for the reaccumulation of dopamine after it has been released. DAT antibodies and antibodies for other markers of catecholamine biosynthesis are widely used as markers for dopaminergic and noradrenergic neurons in a variety of applications including depression, schizophrenia, Parkinson?s disease and drug abuse (Kish et al., 2001, Zhu et al., 2000, Zhu et al., 1999). Levels of DAT protein expression are altered by chronic drug administration (Wilson et al., 1996). Anti-Dopamine Transporter Western blot of human caudate lysate showing specific immunolabeling of the ~88k DAT protein.

Molekulargewicht: '88 kDa

Gen-ID: 6531

UniProt: Q01959

Pathways: Dopaminergic Neurogenesis