YWHAB Antikörper (C-Term)

Produktnummer ABIN361389

Produktdetails anti-YWHAB Antikörper

Target: YWHAB (14-3-3 alpha + beta (YWHAB))

Bindungsspezifität: C-Term

Reaktivität: Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YWHAB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Specific for the ~29k 14-3-3 protein. Immunolabeling of the 14-3-3 protein band is completely blocked by pre-adsorption of the antibody with the C-terminal peptide that was used to generate the antibody.

Kreuzreaktivität: Ratte (Rattus)

Homologie: bovine, canine, chicken, human, mouse, non-human primates, Xenopus, zebra fish

Aufreinigung: Antigen Affinity Purified from Pooled Serum

Immunogen: Synthetic peptide corresponding to amino acid residues from the C-terminal region conjugated to KLH

Anwendungsinformationen

Applikationshinweise: Recommended Dilution: WB: 1:1000 Quality Control: Western blots performed on each lot.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: 100 μL in 10 mM HEPES (  pH 7.5), 150 mM NaCl, 100 μg per ml BSA and 50 % glycerol.

Lagerung: -20 °C

Details zu YWHAB

Target: YWHAB (14-3-3 alpha + beta (YWHAB))

Andere Bezeichnung: YWHAB (YWHAB Produkte)

Synonyme: GW128 antikoerper, HS1 antikoerper, KCIP-1 antikoerper, YWHAA antikoerper, 1300003C17Rik antikoerper, wu:fb22g04 antikoerper, wu:fr86a12 antikoerper, ywhab antikoerper, ywhab2 antikoerper, zgc:64092 antikoerper, 14-3-3beta antikoerper, fb80c08 antikoerper, fk41f08 antikoerper, wu:fb80c08 antikoerper, wu:fd11d01 antikoerper, wu:fk41f08 antikoerper, ywhab1 antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta S homeolog antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta L homeolog antikoerper, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a antikoerper, YWHAB antikoerper, Ywhab antikoerper, ywhabb antikoerper, ywhab.S antikoerper, ywhab.L antikoerper, ywhaba antikoerper

Hintergrund: 14-3-3 proteins are a family of highly conserved proteins that appear to have multiple roles in cell signaling (Bridges and Moorhead, 2005). The proteins are abundantly expressed in the brain and have been detected in the cerebrospinal fluid of patients with different neurological disorders (Berg et al., 2003). 14-3-3 proteins bind protein ligands that are typically phosphorylated on serine or threonine residues and regulate the functions of these binding partners by a number of different mechanisms (Silhan et al., 2004, Dougherty and Morrison, 2004). The 14-3-3 proteins affect a diverse array of cellular processes including the cell cycle and transcription, signal transduction and intracellular trafficking. Anti-14-3-3 Protein Western blot of rat hippocampal (Hipp) lysate showing immunolabeling of the ~29k 14-3-3 protein.

Molekulargewicht: '29 kDa

Gen-ID: 56011

UniProt: P35213

Pathways: Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Myometrial Relaxation and Contraction, Maintenance of Protein Location