CYP7A1
Reaktivität: Human
ELISA
Wirt: Kaninchen
Polyclonal
HRP
Applikationshinweise
ELISA: 1/1,000. Western blotting: 1/50 - 1/100. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
0.25 mg/mL
Buffer
PBS with 0.09 % (W/V) sodium azide
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung
Avoid repeated freezing and thawing.
Lagerung
4 °C/-20 °C
Informationen zur Lagerung
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
Target
CYP7A1
(Cytochrome P450, Family 7, Subfamily A, Polypeptide 1 (CYP7A1))
CP7A antikoerper, CYP7 antikoerper, CYPVII antikoerper, CHAP antikoerper, CYP7S1 antikoerper, cyp7a1a antikoerper, zgc:63920 antikoerper, cytochrome P450 family 7 subfamily A member 1 antikoerper, cytochrome P450, family 7, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 7, subfamily A, polypeptide 1 antikoerper, cholesterol 7-alpha-hydroxylase antikoerper, CYP7A1 antikoerper, Cyp7a1 antikoerper, cyp7a1 antikoerper
Hintergrund
CYP7A1 is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway in the liver, which converts cholesterol to bile acids. This reaction is the rate limiting step and the major site of regulation of bile acid synthesis, which is the primary mechanism for the removal of cholesterol from the body.Synonyms: CYP7, CYPVII, Cholesterol 7-alpha-hydroxylase, Cholesterol 7-alpha-monooxygenase, Cytochrome P450 7A1