ACVR2A Antikörper (N-Term)

Produktnummer ABIN359228

Produktdetails anti-ACVR2A Antikörper

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ACVR2A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody recognizes ACVR2A.

Kreuzreaktivität (Details): Species reactivity (tested):Human.

Aufreinigung: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ACVR2A.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western blotting: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu ACVR2A

Target: ACVR2A (Activin A Receptor, Type IIA (ACVR2A))

Andere Bezeichnung: Activin Receptor Type 2A (ACVR2A) (ACVR2A Produkte)

Synonyme: ACVR2 antikoerper, ACVR2A antikoerper, XSTK9 antikoerper, actrii antikoerper, acvr2 antikoerper, ACTRII antikoerper, Acvr2 antikoerper, rActR-II antikoerper, actr2a antikoerper, acvr2a antikoerper, wu:fa02e10 antikoerper, ActrIIa antikoerper, TactrII antikoerper, activin A receptor type 2A antikoerper, activin A receptor type 2A L homeolog antikoerper, activin A receptor type 2Aa antikoerper, activin receptor IIA antikoerper, ACVR2A antikoerper, acvr2a antikoerper, Acvr2a antikoerper, acvr2a.L antikoerper, acvr2aa antikoerper

Hintergrund: ACVR2A is an activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling, and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.Synonyms: ACTR-IIA, ACTRIIA, Activin A receptor type IIA

Molekulargewicht: 57639 Da

Gen-ID: 92, 9606

UniProt: P27037