STK38 Antikörper (C-Term)

Produktnummer ABIN359159

Produktdetails anti-STK38 Antikörper

Target: STK38 (serine/threonine Kinase 38 (STK38))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser STK38 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Spezifität: This antibody reacts to STK38.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human STK38.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1/250 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu STK38

Target: STK38 (serine/threonine Kinase 38 (STK38))

Andere Bezeichnung: STK38 (STK38 Produkte)

Synonyme: NDR antikoerper, NDR1 antikoerper, 5830476G13Rik antikoerper, 9530097A09Rik antikoerper, AA617404 antikoerper, Ndr1 antikoerper, trc antikoerper, si:ch1073-272h17.2 antikoerper, wu:fj80h03 antikoerper, zgc:55572 antikoerper, serine/threonine kinase 38 antikoerper, serine/threonine kinase 38 S homeolog antikoerper, serine/threonine kinase 38b antikoerper, serine/threonine kinase 38a antikoerper, STK38 antikoerper, Stk38 antikoerper, stk38.S antikoerper, stk38b antikoerper, stk38a antikoerper

Hintergrund: Stk38,also known as NUCLEAR DBF2-RELATED PROTEIN, contains 1 protein kinase domain that interacts with mob1 and mob2.The homodimeric s100b binds to two molecules of stk38. It is ubiquitously expressed with highest levels observed in peripheral blood leukocytes. Stk38 activated by binding of s100b which releases autoinhibitory n-lobe interactions, enabling atp to bind and the autophosphorylation of ser-281. thr-444 then undergoes calcium- dependent phosphorylation by an upstream kinase. Interactions between phosphorylated thr-444 and the n-lobe promote additional structural changes that complete the activation of the kinase. Autoinhibition is also released by the binding of mob1/mobkl1a and mob2/hcca2 to the n-terminal of stk38.Synonyms: NDR1, Nuclear Dbf2-related kinase 1, Serine/threonine-protein kinase 38

Gen-ID: 11329, 9606

UniProt: Q15208