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MAFK Antikörper (C-Term)

MAFK Reaktivität: Human WB, EIA, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN358704
  • Target Alle MAFK Antikörper anzeigen
    MAFK (Transcription Factor MafK (MAFK))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 3
    C-Term
    Reaktivität
    • 27
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 25
    • 2
    Kaninchen
    Klonalität
    • 25
    • 2
    Polyklonal
    Konjugat
    • 12
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    Dieser MAFK Antikörper ist unkonjugiert
    Applikation
    • 21
    • 16
    • 14
    • 6
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Spezifität
    This antibody reacts to MAFK.
    Aufreinigung
    Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MAFK.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product MAFK Primärantikörper
  • Applikationshinweise
    ELISA: 1/1,000. Western blotting: 1/100 - 1/500. Immunohistochemistry: 1/50 - 1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.
  • Target
    MAFK (Transcription Factor MafK (MAFK))
    Andere Bezeichnung
    MAFK (MAFK Produkte)
    Synonyme
    NFE2U antikoerper, P18 antikoerper, AW061068 antikoerper, NF-E2 antikoerper, Nfe2u antikoerper, MAF bZIP transcription factor K antikoerper, v-maf musculoaponeurotic fibrosarcoma oncogene family, protein K (avian) antikoerper, v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog K antikoerper, Mafk antikoerper, MAFK antikoerper, mafk antikoerper
    Hintergrund
    The maf oncogene was identified by structural analysis of the AS42 avian transforming retrovirus genome. The Maf family is divided into two subclasses, large Mafs (vMaf, cMaf, MafB and Nrl) and small Mafs (MafF, MafK, and MafG). Both subclasses contain leucinezipper motifs, which allow homodimerization as well as heterodimerization with a variety of other bZip transcription factors. Large Mafs also contain an acidic transactivation domain absent in the small Maf proteins. Although they do not possess inherent transactivation activity, small Maf proteins can act as positive regulators of transcription by targeting transcriptionally active dimerization partners to specific DNA regulatory elements. Conversely, small Mafs can act also as negative regulators of transcription by recruiting transcriptional repressors or by forming homodimers that can replace active dimers. Human MafF was isolated in a yeast one-hybrid system from a human myometrium cDNA library. Human MAFF encodes a 164 amino acids proten. Like other small MAFF proteins, it contains an extended leucine zipper structure and lacks an N-terminal transactivating domain. The three small Maf proteins have been implicated in a number of physiological processes, including development, differentiation, haematopoiesis and stress response. Interestingly, these three proteins regulate the stress response via different mechanisms.Synonyms: Transcription factor MafK, v-maf musculoaponeurotic fibrosarcoma oncogene homolog K
    Gen-ID
    7975
    NCBI Accession
    NP_002351
    UniProt
    O60675
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