GCNT1 Antikörper (C-Term)

Produktnummer ABIN357692

Produktdetails anti-GCNT1 Antikörper

Target: GCNT1 (Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GCNT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody is specific to GCNT1 (C-term).

Aufreinigung: Protein G Chromatography, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Immunogen: This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GCNT1.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA: 1/1,000. Western Blot: 1/100-1/500. Immunohistochemistry: 1/50-1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu GCNT1

Target: GCNT1 (Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1))

Andere Bezeichnung: GCNT1 / NACGT2 (GCNT1 Produkte)

Synonyme: C2GNT antikoerper, C2GNT-L antikoerper, C2GNT1 antikoerper, G6NT antikoerper, NACGT2 antikoerper, NAGCT2 antikoerper, 5630400D21Rik antikoerper, B130048E03 antikoerper, C2 GlcNAcT antikoerper, IGnT antikoerper, core 2 GlcNAc-T antikoerper, glucosaminyl (N-acetyl) transferase 1, core 2 L homeolog antikoerper, glucosaminyl (N-acetyl) transferase 1, core 2 antikoerper, gcnt1.L antikoerper, GCNT1 antikoerper, Gcnt1 antikoerper

Hintergrund: Glycosylation is one of the most universal but at the same time complex protein modifications. Modification with sugar moeties can be both co- translational and post- translational, occurring in the endoplasmatic reticulum and golgi. Three different forms of glycosylation can be distinguished: N-linked oligosaccharides, O-linked oligosaccharides and glycosyl- phosphatidylinositol (GPI-) anchors. Glycosylation results in thousands of distinct, bioactive glycoproteins resident throughout the cell that strongly determine protein-protein, carbohydrate-protein, membrane, and adhesion properties. Diseases associated with glycosylation defects include Congenital disorders of glycosylation, (CDG), also known as carbohydrate deficient glycoprotein syndromes, and diseases associated with advanced aging.Synonyms: 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase, Beta-1, C2GNT, Core 2 GNT, Core 2-branching enzyme, Core2-GlcNAc-transferase

Molekulargewicht: 49784 Da

Gen-ID: 2650, 5874

UniProt: Q02742