GJB6 Antikörper (N-Term)

Produktnummer ABIN357095

Produktdetails anti-GJB6 Antikörper

Target: GJB6 (Gap Junction Protein, beta 6, 30kDa (GJB6))

Bindungsspezifität: AA 95-124, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GJB6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)

Spezifität: This antibody detects GJB6 at N-term.

Aufreinigung: Protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide between 95~124 amino acids from the N-terminal region of Human GJB6.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: ELISA 1: 1,000. Immunohistochemistry 1: 50 - 1: 100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) Sodium Azide as preservative

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer.

Details zu GJB6

Target: GJB6 (Gap Junction Protein, beta 6, 30kDa (GJB6))

Andere Bezeichnung: GJB6 / Cx30 (GJB6 Produkte)

Synonyme: connexin-26 antikoerper, cx26 antikoerper, cx30 antikoerper, dfna3 antikoerper, dfna3a antikoerper, dfnb1 antikoerper, dfnb1a antikoerper, ed2 antikoerper, edh antikoerper, gjb6 antikoerper, hed antikoerper, nsrd1 antikoerper, ppk antikoerper, AA958971 antikoerper, Cx30 antikoerper, D14Bwg0506e antikoerper, CX30 antikoerper, DFNA3 antikoerper, DFNA3B antikoerper, DFNB1B antikoerper, ECTD2 antikoerper, ED2 antikoerper, EDH antikoerper, HED antikoerper, HED2 antikoerper, CX31 antikoerper, connexin 30 antikoerper, gap junction protein beta 2 antikoerper, gap junction protein beta 6 antikoerper, gap junction protein, beta 6 antikoerper, LOC387566 antikoerper, gjb2 antikoerper, GJB6 antikoerper, Gjb6 antikoerper

Hintergrund: Gap junctions are conduits that allow the direct cell-to-cell passage of small cytoplasmic molecules, including ions, metabolic intermediates, and second messengers, and thereby mediate intercellular metabolic and electrical communication. Gap junction channels consist of connexin protein subunits, which are encoded by a multigene family. GJBs (gap-junction proteins or connexins) play crucial functional roles associated with these channels. I Mutations in GJB2 are associated with genetically derived hearing impairments, including autosomal dominant, bilateral, middle to high frequency hearing loss.Synonyms: Connexin-30, Gap junction beta-6 protein

Molekulargewicht: 30387 Da

Gen-ID: 10804, 9606

UniProt: O95452

Pathways: Sensory Perception of Sound