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ALPL Antikörper (N-Term)

ALPL Reaktivität: Human, Maus WB, EIA Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN356989
  • Target Alle ALPL Antikörper anzeigen
    ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))
    Bindungsspezifität
    • 16
    • 14
    • 9
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 85
    • 49
    • 17
    • 5
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus
    Wirt
    • 82
    • 19
    • 1
    • 1
    Kaninchen
    Klonalität
    • 82
    • 21
    Polyklonal
    Konjugat
    • 61
    • 10
    • 7
    • 5
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ALPL Antikörper ist unkonjugiert
    Applikation
    • 75
    • 43
    • 27
    • 18
    • 13
    • 13
    • 13
    • 12
    • 11
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Spezifität
    This antibody detects Alkaline Phosphatase at N-term.
    Aufreinigung
    Protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS
    Immunogen
    This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human ALPL.
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product ALPL Primärantikörper
  • Applikationshinweise
    ELISA 1: 1,000. Western blot 1: 50 - 1: 100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) sodium azide
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
  • Target
    ALPL (Alkaline Phosphatase, Liver/bone/kidney (ALPL))
    Andere Bezeichnung
    Alkaline Phosphatase / ALPL (ALPL Produkte)
    Synonyme
    ALP antikoerper, iap antikoerper, alpl antikoerper, AP-TNAP antikoerper, APTNAP antikoerper, HOPS antikoerper, TNAP antikoerper, TNSALP antikoerper, Akp-2 antikoerper, Akp2 antikoerper, PHOA antikoerper, TNS-AP antikoerper, alkaline phosphatase, liver/bone/kidney L homeolog antikoerper, alkaline phosphatase, liver/bone/kidney antikoerper, alkaline phosphatase, intestinal, gene 2 antikoerper, alkaline phosphatase, liver/bone/kidney pseudogene antikoerper, alpl.L antikoerper, ALPL antikoerper, alpi.2 antikoerper, LOC100031702 antikoerper, Alpl antikoerper
    Hintergrund
    There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The genes for the first three are located together on chromosome 2 while the tissue non-specific form is located on chromosome 1. This protein is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme. The exact physiological function of the alkaline phosphatases is not known. A proposed function of this form of the enzyme is matrix mineralization, however, mice that lack a functional form of this enzyme show normal skeletal development. This enzyme has been linked directly to a disorder known as hypophosphatasia, a disorder that is characterized by hypercalcemia and includes skeletal defects. The character of this disorder can vary, however, depending on the specific mutation since this determines age of onset and severity of symptoms.Synonyms: AP-TNAP, Alkaline phosphatase, Alkaline phosphatase liver/bone/kidney isozyme, TNSALP, tissue-nonspecific isozyme
    Molekulargewicht
    57323 Da
    Gen-ID
    249, 9606
    UniProt
    P05186
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