OMP Antikörper (Olfactory Marker Protein)

Details for Product anti-OMP Antibody No. ABIN350659, Anbieter: Anmelden zum Anzeigen
Antigen
  • omp
  • zgc:101697
  • xomp1
  • xomp2
  • omp2-A
  • MGC75776
  • OMP
  • olfactory marker protein b
  • olfactory marker protein L homeolog
  • olfactory marker protein S homeolog
  • olfactory marker protein
  • ompb
  • omp.L
  • omp.S
  • omp
  • OMP
  • Omp
Reaktivität
Ratte (Rattus), Maus
43
22
21
4
2
2
1
Wirt
Schaf
45
6
6
4
3
Klonalität
Polyklonal
Konjugat
Dieser OMP Antikörper ist unkonjugiert
4
4
4
2
2
2
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
53
28
21
3
1
1
1
Optionen
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Immunogen A synthetic peptide from rat OMP conjugated to blue carrier protein has been used as the antigen. The peptide is homologous in mouse.
Spezifität Highly specific for mature olfactory neurons (including axon and terminals).
Reinigung Whole serum
Plasmids, Primers & others Plasmide, Primers & weitere OMP products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung OMP (OMP Antibody Abstract)
Hintergrund Olfactory marker protein (OMP) is an abundant, 19-kDa, cytosolic protein that is almost exclusively expressed in mature, functioning,olfactory neurons but not in the neural precursor basal cells. The OMP gene structure and protein sequence are highly conserved between mouse, rat and human. Its tissue-specific expression in the receptor cells together with the results of the mouse knockout studies show that OMP represents a novel modulatory component of the odor detection/signal transduction cascade.
Function: May act as a modulator of theolfactory signal-transduction cascade.
Subunit: Interacts with BEX1 and BEX2.
Subcellular location: Cytoplasm.
Tissue specificity: Uniquely associated with matureolfactory receptor neurons. SIMILARITY: Belongs to theolfactory marker protein family. Also known as:olfactory neuronal-specificprotein.
Applikations-hinweise Use at a dilution of 1 : 200 to 1 : 2000.
The optimal dilution should be determined by the end user. For IHC, Zamboni's or 4% PFA fixatives are recommended.
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Lyophilized
Rekonstitution Reconstitute in 100 µL of sterile water. Centrifuge to remove any insoluble material.
Handhabung Avoid freeze and thaw cycles.
Lagerung 4 °C/-20 °C
Informationen zur Lagerung Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Haltbarkeit 12 months
Bilder des Herstellers
 image for anti-Olfactory Marker Protein (OMP) antibody (ABIN350659) IF on rat olfactory bulb using Rabbit antibody to cFos (c-fos): whole serum (ABIN3502...
 image for anti-Olfactory Marker Protein (OMP) antibody (ABIN350659) IF on rat olfactory bulb using Rabbit antibody to cFos (c-fos): whole serum (ABIN3502...
 image for anti-Olfactory Marker Protein (OMP) antibody (ABIN350659) IF on rat olfactory bulb using Sheep antibody to rat & mouse OMP (Olfactory Marker Pr...
Immunofluorescence (IF) image for anti-Olfactory Marker Protein (OMP) antibody (ABIN350659) IF on rat olfactory bulb using Rabbit antibody to c Fos (OSR00004W) at a 1 : 500 dilu...
Allgemeine Veröffentlichungen Moriya-Ito, Osada, Ishimatsu, Muramoto, Kobayashi, Ichikawa: "Maturation of vomeronasal receptor neurons in vitro by coculture with accessory olfactory bulb neurons." in: Chemical senses, Vol. 30, Issue 2, pp. 111-9, 2005 (PubMed).

Baldisseri, Margolis, Weber, Koo, Margolis: "Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction." in: Journal of molecular biology, Vol. 319, Issue 3, pp. 823-37, 2002 (PubMed).

Walters, Grillo, Oestreicher, Margolis: "LacZ and OMP are co-expressed during ontogeny and regeneration in olfactory receptor neurons of OMP promoter-lacZ transgenic mice." in: International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience, Vol. 14, Issue 7-8, pp. 813-22, 1997 (PubMed).

Margolis: "Olfactory marker protein (OMP)." in: Scandinavian journal of immunology. Supplement, Vol. 9, pp. 181-99, 1983 (PubMed).

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