SLC1A3 Antikörper (C-Term)

Produktnummer ABIN350311

Produktdetails anti-SLC1A3 Antikörper

Target: SLC1A3 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3))

Bindungsspezifität: C-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC1A3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: Specific for EAAT1.

Kreuzreaktivität: Maus, Ratte

Kreuzreaktivität (Details): Other species not yet tested.

Aufreinigung: IgG

Immunogen: A synthetic peptide from c-terminal region of mouse EAAT1 conjugated to blue carrier protein was used as the antigen. The antigen is homologous in rat.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC, WB. A concentration of 10-50 μg,ml is recommended. The optimal concentration should be determined by the end user. Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Reconstitute in 500 μL of sterile water. Centrifuge to remove any insoluble material.

Handhabung: Avoid freeze and thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Maintain the lyophilised/reconstituted antibodies frozen at -20°C for long term storage and refrigerated at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.

Haltbarkeit: 12 months

Details zu SLC1A3

Target: SLC1A3 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3 (SLC1A3))

Andere Bezeichnung: SLC1A3 (SLC1A3 Produkte)

Synonyme: AF001784 antikoerper, CG3747 antikoerper, Dglt-1 antikoerper, Dglut-1 antikoerper, Dmel\\CG3747 antikoerper, EAAT antikoerper, EAAT1 antikoerper, dEAAT antikoerper, dEAAT1 antikoerper, dEaat1 antikoerper, slc1a3 antikoerper, wu:fb98e05 antikoerper, wu:fd50b05 antikoerper, zgc:56661 antikoerper, zgc:77768 antikoerper, SLC1A3 antikoerper, GLAST antikoerper, GluT-1 antikoerper, EA6 antikoerper, GLAST1 antikoerper, AI504299 antikoerper, B430115D02Rik antikoerper, Eaat1 antikoerper, GLAST-1 antikoerper, GLU-T antikoerper, Gmt1 antikoerper, MGluT1 antikoerper, Excitatory amino acid transporter 1 antikoerper, solute carrier family 1 member 3 antikoerper, excitatory amino acid transporter 1 antikoerper, solute carrier family 1 (glial high affinity glutamate transporter), member 3a antikoerper, solute carrier family 1 (glial high affinity glutamate transporter), member 3 antikoerper, Eaat1 antikoerper, SLC1A3 antikoerper, PTRG_00379 antikoerper, Tsp_02392 antikoerper, slc1a3a antikoerper, Slc1a3 antikoerper

Hintergrund: FUNCTION: Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Defects in SLC1A3 are the cause of episodic ataxia type 6 (EA6). EA6 is characterized by episodic ataxia, seizures, migraine and alternating hemiplegia. SUBCELLULAR LOCATION: Membrane, Multi-pass membrane protein. TISSUE SPECIFICITY: Highly expressed in cerebellum, but also found in frontal cortex, hippocampus and basal ganglia.,SLC1 Family,Sodium-dependent glutamate/aspartate transporter 1, GLAST-1, Solute carrier family 1 member 3, SLC1A3, EAAT1, GLAST, GLAST1

UniProt: P56564

Pathways: Sensory Perception of Sound, Synaptic Membrane, Dicarboxylic Acid Transport