Maus anti-Human IgG (Fab Region) Antikörper (PE)

Details zu Produkt Nr. ABIN349709, Anbieter: Anmelden zum Anzeigen
Antigen
Epitop
Fab Region
6301
1957
1801
1065
889
727
374
301
35
34
31
15
11
7
3
3
1
1
1
1
1
1
1
Reaktivität
Human
3070
2885
2378
1634
1479
785
690
459
456
397
369
364
301
288
280
146
128
114
42
34
29
26
16
15
11
10
8
7
5
5
4
4
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
Wirt
Maus
6986
5099
1927
1048
534
360
89
84
55
35
23
15
8
5
3
1
1
Klonalität (Klon)
Monoklonal ()
Konjugat
PE
2225
1808
1765
1261
763
687
455
309
196
155
155
150
127
122
122
102
102
96
94
89
84
79
78
75
73
68
68
68
65
61
55
55
54
54
54
53
53
53
53
53
53
53
48
48
41
38
35
34
31
24
23
23
22
20
18
18
17
16
15
15
15
14
14
14
14
14
12
12
12
12
11
10
10
10
10
10
9
9
9
9
8
8
8
8
8
7
6
6
6
6
6
5
5
5
5
5
5
4
4
4
4
4
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Applikation
Flow Cytometry (FACS)
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Purified human IgG.
Klon 4A11
Isotyp IgG2b
Spezifität The antibody 4A11 reacts with Fab fragment of human IgG.
Produktmerkmale The purified antibody is conjugated with R-Phycoerythrin (PE) under optimum conditions. The conjugate is purified by size-exclusion chromatography and adjusted for direct use.
Antigen
Hintergrund Immunoglobulin G (IgG) is a 150 kDa soluble protein that serves as a major effector molecule of the humoral immune response in man. Its concentration in blood plasma of healthy individuals is approximately 10 g/l, which accounts for about 75 % of the total plasma immunoglobulins. IgG has the highest stability of blood immunoglobulins (T1/2 = 21 days) and is able of placental transfer. IgG is secreted by plasma cells at a comparably high rate as other immunoglobulins.
Molekulargewicht 150 kDa
Applikations-hinweise The reagent is designed for Flow Cytometry analysis. Suggested working dilution is 6 µg/mL. Indicated dilution is recommended starting point for use of this product. Working concentrations should be determined by the investigator.

Working concentrations should be determined by the investigator.
Kommentare

Excitation/Emission wavelength: 496 nm/576 nm

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Rekonstitution No reconstitution is necessary.
Konzentration 0.1 mg/mL
Buffer The reagent is provided in phosphate buffered saline (PBS) containing 15 mM sodium azide and 0.2 % (w/v) high-grade protease free Bovine Serum Albumin (BSA) as a stabilizing agent.
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Do not freeze.
Avoid prolonged exposure to light.
Lagerung 4 °C
Informationen zur Lagerung Store in the dark at 2-8 °C. Do not use after expiration date stamped on vial label. Short-term exposure to room temperature should not affect the quality of the reagent. However, if reagent is stored under any conditions other than those specified, the conditions must be verified by the user.
Bilder des Herstellers
Western Blotting (WB) image for Mouse anti-Human IgG (Fab Region) antibody (PE) (ABIN349709) Western Blotting analysis (reducing conditions) of human IgG Fab fragment using anti-...
Allgemeine Veröffentlichungen Brinkmann, Heusser: "T cell-dependent differentiation of human B cells into IgM, IgG, IgA, or IgE plasma cells: high rate of antibody production by IgE plasma cells, but limited clonal expansion of IgE precursors." in: Cellular immunology, Vol. 152, Issue 2, pp. 323-32, 1994 (PubMed).

Balogh, Merétey, Falus, Bozsóky: "Serological abnormalities in juvenile chronic arthritis: a review of 46 cases." in: Annals of the rheumatic diseases, Vol. 39, Issue 2, pp. 129-34, 1980 (PubMed).

Fuller, Keyser: "Serum immunoglobulins after surgical operation." in: Clinical chemistry, Vol. 21, Issue 6, pp. 667-71, 1975 (PubMed).

Franklin: "Structure and function of immunoglobulins." in: Acta endocrinologica. Supplementum, Vol. 194, pp. 77-95, 1975 (PubMed).