Mu Opioid Receptor 1 Antikörper

Produktnummer ABIN317766

Produktdetails anti-Mu Opioid Receptor 1 Antikörper

Target: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Mu Opioid Receptor 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of MOR-1 protein.(region surrounding Ser57)

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Mu Opioid Receptor 1

Target: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Andere Bezeichnung: OPRM1 (OPRM1 Produkte)

Synonyme: LMOR antikoerper, M-OR-1 antikoerper, MOP antikoerper, MOR antikoerper, MOR1 antikoerper, OPRM antikoerper, MOP-R antikoerper, MOR-1 antikoerper, MOR-1O antikoerper, Oprm antikoerper, mor antikoerper, muOR antikoerper, MORA antikoerper, Oprrm1 antikoerper, or2 antikoerper, ZFOR2 antikoerper, OPRM1 antikoerper, opioid receptor mu 1 antikoerper, opioid receptor, mu 1 antikoerper, outer membrane protein OprM antikoerper, OPRM1 antikoerper, Oprm1 antikoerper, oprm1 antikoerper, oprM1 antikoerper

Hintergrund: Three types of opioid receptors have been cloned: mu, delta, and kappa. Opioid receptors are seven transmembrane G-protein coupled receptors. They share a high degree of homology and are most divergent at the N- and C-termini. Activation of mu opioid receptors leads to a decrease in neuronal excitability. Most actions of exogenous opioids, such as morphine, are mediated through the μ-opioid receptor, including analgesia, tolerance and reward. In general, opioids modulate numerous central and peripheral processes including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidylinositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities.Synonyms: MOR1, Mu-type opioid receptor

Molekulargewicht: approx. 48 kDa

Gen-ID: 4988

NCBI Accession: NP_000905

UniProt: P35372

Pathways: cAMP Metabolic Process, Synaptic Membrane