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Prostate Specific Antigen Antikörper (AA 26-251)

Name: Prostate Specific Antigen Antikörper (AA 26-251)
Brand: antibodies-online
SKU: ABIN969369
Price: 562.94 EUR
Availability: InStock

PSA Reaktivität: Human ELISA, WB, IHC, FACS Wirt: Maus Monoclonal 5A11E9 unconjugated

Immunohistochemical analysis of paraffin-embedded human prostate tissues using KLK3 mouse mAb with DAB staining.

IHC

Flow cytometric analysis of PC-3 cells using KLK3 mouse mAb (right) and negative control (left).

FACS

Immunohistochemical analysis of paraffin-embedded human prostate carcinoma tissues, showing cytoplasmic localization using KLK3 mouse mAb with DAB staining.

IHC

Western blot analysis using KLK3 mouse mAb against truncated KLK3 recombinant protein.

4 Abbildungen

(2 Referenzen)

Produktnummer ABIN969369

Datenblatt (PDF)

Target Alle Prostate Specific Antigen (PSA) Antikörper anzeigen

Prostate Specific Antigen (PSA)
Bindungsspezifität
16

7

5

5

5

5

5

5

3

2

2

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1

1
AA 26-251
Reaktivität
188

15

10

5

4

1
Human
Wirt
117

64

4

4

2
Maus
Passende Sekundärantikörper
Klonalität
130

61
Monoklonal
Konjugat
100

17

13

7

6

5

5

5

5

5

5

3

2

2

2

2

2

1

1

1

1

1

1

1
Dieser Prostate Specific Antigen Antikörper ist unkonjugiert
Applikation
89

76

37

36

26

25

24

14

13

9

9

9

8

5

4

4

3

2

2

2

2

2

2

1

1

1

1

1
ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)

Aufreinigung

purified

Immunogen

Purified recombinant fragment of KLK3 (aa26-251) expressed in E. coli.

Klon

5A11E9

Isotyp

IgG1

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Applikationshinweise

ELISA: 1:10000, WB: 1:500 - 1:2000, IHC: 1:200 - 1:1000, FCM: 1:200 - 1:400

Beschränkungen

Nur für Forschungszwecke einsetzbar
Format

Liquid

Buffer

Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel

Sodium azide

Vorsichtsmaßnahmen

This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung

4 °C/-20 °C

Informationen zur Lagerung

4°C, -20°C for long term storage
Alzghoul, Hailat, Zivanovic, Que, Shah: "Measurement of serum prostate cancer markers using a nanopore thin film based optofluidic chip." in: Biosensors & bioelectronics, Vol. 77, pp. 491-8, (2015) (PubMed).

Hassan, Kumar, Singh, Yadav: "Structural model of human PSA: a target for prostate cancer therapy." in: Chemical biology & drug design, Vol. 70, Issue 3, pp. 261-7, (2007) (PubMed).
Target

Prostate Specific Antigen (PSA)

Andere Bezeichnung

PSA (KLK3) (PSA Produkte)

Synonyme

APS antikoerper, KLK2A1 antikoerper, PSA antikoerper, hK3 antikoerper, KLK3 antikoerper, Klk1c10l2 antikoerper, RSGK-50 antikoerper, RSKG-50 antikoerper, rGK-3 antikoerper, Kal-3 antikoerper, Kal3 antikoerper, Klk3 antikoerper, AAP-S antikoerper, MP100 antikoerper, Psa antikoerper, R74825 antikoerper, goku antikoerper, kallikrein related peptidase 3 antikoerper, kallikrein 3 antikoerper, kallikrein 1-related peptidase C3 antikoerper, kallikrein B, plasma 1 antikoerper, aminopeptidase puromycin sensitive antikoerper, KLK3 antikoerper, Klk1c3 antikoerper, Klkb1 antikoerper, Npepps antikoerper

Hintergrund

Description: Kallikrein-related peptidase 3.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.
Aliases: APS, PSA, hK3, KLK2A1, KLK3

Gen-ID

354

HGNC

354

Pathways

Komplementsystem