NPDC1 Antikörper

Produktnummer ABIN306963

Produktdetails anti-NPDC1 Antikörper

Target: NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser NPDC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: Monoclonal Anti-NPDC-1 (mouse IgG1 isotype) is derived from the hybridoma 16E4 produced by immunizing mice with the peptide SLGSPVSSDPVHMS (Gene ID: 56654).

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: The discovery of NPDC-1 (neuronal proliferation, differentiation and control protein 1) was the result of a study of genes that were preferentially expressed in immortalized neural precursor cell lines at the onset of contact inhibition of proliferation and subsequent differentiation. It was further found that transfection of transformed cells with NPDC-1 led to increased doubling times and suppression of many characteristics of transformation. NPDC-1 is differentially expressed in brain and lung and has been shown to interact directly with the transcription factor E2F-1 as well as D-type cyclins and cdk2. NPDC-1 has been identified as a modulator of transcriptional events mediated by retinoic acid and the protein level and activity of NPDC-1 have been shown to be regulated by phosphorylation mediated proteasomal degradation.

Aufreinigung: Ion-exchange chromatography

Immunogen: Hybridoma produced by the fusion of splenocytes from mice immunized with a synthetic peptide SLGSPVSSDPVHMS derived from human NPDC-1 protein (Gene ID: 56654) and mouse myeloma cells.

Klon: 16E4

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Antibody can be used for Western blotting (1:1000 dilution). Optimal concentration should be evaluated by serial dilutions. Monoclonal Anti-NPDC-1 recognizes human NPDC-1 by immunoblotting (34-40 kDa).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: 20 mM sodium phosphate, 150 mM sodium chloride, 50 % glycerol, pH 7.5, 3 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu NPDC1

Target: NPDC1 (Neural Proliferation, Differentiation and Control, 1 (NPDC1))

Andere Bezeichnung: NPDC-1 (NPDC1 Produkte)

Synonyme: AI314472 antikoerper, NPDC-1 antikoerper, CAB antikoerper, CAB- antikoerper, CAB-1 antikoerper, CAB1 antikoerper, neural proliferation, differentiation and control, 1, gene 1 L homeolog antikoerper, neural proliferation, differentiation and control 1 antikoerper, neural proliferation, differentiation and control, 1 antikoerper, npdc1.1.L antikoerper, Npdc1 antikoerper, NPDC1 antikoerper

UniProt: Q8WXX4