FADD Antikörper (Fas (TNFRSF6)-Associated Via Death Domain)

Details for Product anti-FADD Antibody No. ABIN306466, Anbieter: Anmelden zum Anzeigen
Antigen
  • MORT1
  • Mort1/FADD
  • Mort1
  • TNFRSF6
  • adaptor
  • fadd
  • mort1
  • xfadd
  • Fas associated via death domain
  • Fas (TNFRSF6)-associated via death domain
  • Fas associated via death domain S homeolog
  • Fas (tnfrsf6)-associated via death domain
  • FADD
  • Fadd
  • fadd.S
  • fadd
Reaktivität
Human
218
91
38
10
2
2
Wirt
Maus
196
82
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser FADD Antikörper ist unkonjugiert
10
9
9
4
4
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
249
141
102
50
28
18
15
10
5
4
4
4
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Recombinant human FADD (1-208aa), Accession / GI number: NP_003815
Klon J1D2
Isotyp IgG2b, kappa
Reinigung The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
Plasmids, Primers & others Plasmide, Primers & weitere FADD products on genomics-online (e.g. as negative or positive controls)
Antigen
Andere Bezeichnung FADD (FADD Antibody Abstract)
Hintergrund FADD (Fas-associated protein with death domain) is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. This protein is implicated in survival/proliferation and cell cycle progression. FADD functions are also regulated via cellular sublocalization, protein phosphorylation, and inhibitory molecules.
Pathways Apoptose, TLR Signalweg, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
Applikations-hinweise Recommended dilution 1:1000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1mg/ml
Buffer In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Bilder des Herstellers
Western Blotting (WB) image for anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibody (ABIN306466) anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibody
Immunohistochemistry (IHC) image for anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibody (ABIN306466) Paraffin embedded sections of human breast cancer tissue were incubated with anti-hum...
Immunofluorescence (IF) image for anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibody (ABIN306466) ICC/IF analysis of FADD in HeLa cells line, stained with DAPI (Blue) for nucleus stai...
Allgemeine Veröffentlichungen Tsao, Su, Lin, Yu, Kuo, Shen, Chen, Liao: "Japanese encephalitis virus infection activates caspase-8 and -9 in a FADD-independent and mitochondrion-dependent manner." in: The Journal of general virology, Vol. 89, Issue Pt 8, pp. 1930-41, 2008 (PubMed).

Tourneur, Buzyn, Chiocchia: "FADD adaptor in cancer." in: Medical immunology (London, England), Vol. 4, Issue 1, pp. 1, 2005 (PubMed).

Bannerman, Tupper, Kelly, Winn, Harlan: "The Fas-associated death domain protein suppresses activation of NF-kappa B by LPS and IL-1 beta." in: The Journal of clinical investigation, Vol. 109, Issue 3, pp. 419-25, 2002 (PubMed).

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