FADD Antikörper (Fas (TNFRSF6)-Associated Via Death Domain)

Details for Product anti-FADD Antibody No. ABIN306466, Anbieter: Anmelden zum Anzeigen
Antigen
  • MORT1
  • Mort1/FADD
  • Mort1
  • TNFRSF6
  • adaptor
  • fadd
  • mort1
  • xfadd
  • Fas associated via death domain
  • Fas (TNFRSF6)-associated via death domain
  • Fas associated via death domain S homeolog
  • Fas (tnfrsf6)-associated via death domain
  • FADD
  • Fadd
  • fadd.S
  • fadd
Reaktivität
Human
223
80
37
11
3
2
Wirt
Maus
177
99
Klonalität (Klon)
Monoklonal ()
Konjugat
Dieser FADD Antikörper ist unkonjugiert
11
10
10
7
7
5
3
3
3
2
2
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
Applikation
ELISA, Western Blotting (WB)
249
145
86
50
32
18
15
8
5
4
4
3
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen Recombinant human FADD (1-208aa), Accession / GI number: NP_003815
Klon J1D2
Isotyp IgG2b, kappa
Reinigung The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography
Andere Bezeichnung FADD (FADD Antibody Abstract)
Hintergrund FADD (Fas-associated protein with death domain) is an adaptor molecule that interacts with various cell surface receptors and mediates cell apoptotic signals. This protein is implicated in survival/proliferation and cell cycle progression. FADD functions are also regulated via cellular sublocalization, protein phosphorylation, and inhibitory molecules.
Pathways Apoptose, TLR Signalweg, Activation of Innate immune Response, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades
Applikations-hinweise Recommended dilution 1:1000
Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration 1mg/ml
Buffer In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide
Konservierungs-mittel Sodium azide
Vorsichtsmaßnahmen This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung -20 °C
Bilder des Herstellers
Western Blotting (WB) image for anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibody (ABIN306466) anti-Fas (TNFRSF6)-Associated Via Death Domain (FADD) antibody
Allgemeine Veröffentlichungen Tsao, Su, Lin, Yu, Kuo, Shen, Chen, Liao: "Japanese encephalitis virus infection activates caspase-8 and -9 in a FADD-independent and mitochondrion-dependent manner." in: The Journal of general virology, Vol. 89, Issue Pt 8, pp. 1930-41, 2008 (PubMed).

Tourneur, Buzyn, Chiocchia: "FADD adaptor in cancer." in: Medical immunology (London, England), Vol. 4, Issue 1, pp. 1, 2005 (PubMed).

Bannerman, Tupper, Kelly, Winn, Harlan: "The Fas-associated death domain protein suppresses activation of NF-kappa B by LPS and IL-1 beta." in: The Journal of clinical investigation, Vol. 109, Issue 3, pp. 419-25, 2002 (PubMed).

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