TRIB2 Antikörper (Middle Region)

Produktnummer ABIN3044555

Produktdetails anti-TRIB2 Antikörper

Target: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Bindungsspezifität: AA 175-211, Middle Region

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRIB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Tribbles homolog 2(TRIB2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Sequenz: DLKLRKFIFK DEERTRVKLE SLEDAYILRG DDDSLSD

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Tribbles homolog 2(TRIB2) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: tribbles pseudokinase 2
Protein Name: Tribbles homolog 2

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human TRIB2 (175-211aa DLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSD), identical to the related mouse sequence.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu TRIB2

Target: TRIB2 (Tribbles Pseudokinase 2 (TRIB2))

Andere Bezeichnung: TRIB2 (TRIB2 Produkte)

Synonyme: TRIB2 antikoerper, Trb2 antikoerper, Xtrbl antikoerper, gs3955 antikoerper, c5fw antikoerper, trb2 antikoerper, xtrb2 antikoerper, TRB2 antikoerper, C5FW antikoerper, GS3955 antikoerper, TRB-2 antikoerper, AW319517 antikoerper, RGD1564451 antikoerper, tribbles pseudokinase 2 antikoerper, tribbles pseudokinase 2 S homeolog antikoerper, TRIB2 antikoerper, trib2 antikoerper, trib2.S antikoerper, Trib2 antikoerper

Hintergrund: Tribbles homolog 2 is a protein that in humans is encoded by the TRIB2 gene. This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBP alpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene.

Synonyms: C5FW antibody|FLJ57420 antibody|GS3955 antibody|Hypothetical protein TRB2 antibody|TRB-2 antibody|TRB2 antibody|TRIB 2 antibody|TRIB2 antibody|TRIB2_HUMAN antibody|Tribbles homolog 2 antibody

Gen-ID: 28951

UniProt: Q92519