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TNFSF8 Antikörper (AA 63-234)

TNFSF8 Reaktivität: Human FACS, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3044499
  • Target Alle TNFSF8 Antikörper anzeigen
    TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))
    Bindungsspezifität
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 63-234
    Reaktivität
    • 35
    • 26
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 35
    • 8
    • 6
    Kaninchen
    Klonalität
    • 36
    • 12
    • 1
    Polyklonal
    Konjugat
    • 31
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser TNFSF8 Antikörper ist unkonjugiert
    Applikation
    • 33
    • 14
    • 11
    • 11
    • 6
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Tumor necrosis factor ligand superfamily member 8(TNFSF8) detection. Tested with IHC-P, FCM in Human.
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Tumor necrosis factor ligand superfamily member 8(TNFSF8) detection. Tested with IHC-P, FCM in Human.
    Gene Name: tumor necrosis factor superfamily member 8
    Protein Name: Tumor necrosis factor ligand superfamily member 8
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human CD153 recombinant protein (Position: Q63-D234). Human CD153 shares 75% amino acid (aa) sequence identity with mouse CD153.
    Isotyp
    IgG
    Top Product
    Discover our top product TNFSF8 Primärantikörper
  • Applikationshinweise
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Flow Cytometry: Concentration:1-3 μg/1x106 cells, Tested Species: Human
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    TNFSF8 (Tumor Necrosis Factor (Ligand) Superfamily, Member 8 (TNFSF8))
    Andere Bezeichnung
    TNFSF8 (TNFSF8 Produkte)
    Synonyme
    CD153 antikoerper, CD30LG antikoerper, Cd30l antikoerper, CD30L antikoerper, TNFRSF8 antikoerper, TNFSF8 antikoerper, tumor necrosis factor (ligand) superfamily, member 8 antikoerper, TNF superfamily member 8 antikoerper, tumor necrosis factor superfamily member 8 antikoerper, Tnfsf8 antikoerper, TNFSF8 antikoerper
    Hintergrund
    CD153 is a ligand for CD30. The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene.

    Synonyms: CD153 antibody|CD153 antigen antibody|CD30 antigen ligand antibody|CD30 L antibody|CD30 ligand antibody|CD30-L antibody|CD30L antibody|CD30LG antibody|MGC138144 antibody|TNFL8_HUMAN antibody|Tnfsf8 antibody|Tumor necrosis factor (ligand) superfamily member 8 antibody|Tumor necrosis factor ligand superfamily member 8 antibody
    Gen-ID
    944
    UniProt
    P32971
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