GABRA1 Antikörper (C-Term)
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- Target Alle GABRA1 Antikörper anzeigen
- GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
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Bindungsspezifität
- AA 440-456, C-Term
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Reaktivität
- Ratte, Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser GABRA1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Gamma-aminobutyric acid receptor subunit alpha-1(GABRA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
- Sequenz
- ATYLNREPQL KAPTPHQ
- Kreuzreaktivität (Details)
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Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities. - Produktmerkmale
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Rabbit IgG polyclonal antibody for Gamma-aminobutyric acid receptor subunit alpha-1(GABRA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: gamma-aminobutyric acid(GABA) A receptor, alpha 1
Protein Name: Gamma-aminobutyric acid receptor subunit alpha-1 - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of human GABA A Receptor alpha 1(440-456aa ATYLNREPQLKAPTPHQ), identical to the related rat and mouse sequences.
- Isotyp
- IgG
- Top Product
- Discover our top product GABRA1 Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Konservierungsmittel
- Thimerosal (Merthiolate), Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Haltbarkeit
- 12 months
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Role of microRNA-4458 in patients with non-small-cell lung cancer." in: Oncology letters, Vol. 12, Issue 5, pp. 3958-3966, (2016) (PubMed).
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Role of microRNA-4458 in patients with non-small-cell lung cancer." in: Oncology letters, Vol. 12, Issue 5, pp. 3958-3966, (2016) (PubMed).
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- Target
- GABRA1 (gamma-aminobutyric Acid (GABA) A Receptor, alpha 1 (GABRA1))
- Andere Bezeichnung
- GABRA1 (GABRA1 Produkte)
- Synonyme
- ECA4 antikoerper, EJM antikoerper, EJM5 antikoerper, zgc:153566 antikoerper, Gabra-1 antikoerper, gamma-aminobutyric acid type A receptor alpha1 subunit antikoerper, gamma-aminobutyric acid (GABA) A receptor, alpha 1 antikoerper, gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1 antikoerper, gamma-aminobutyric acid receptor subunit alpha-1 antikoerper, GABRA1 antikoerper, Gabra1 antikoerper, gabra1 antikoerper, LOC100653509 antikoerper
- Hintergrund
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GABRA1, Gamma-aminobutyric acid receptor subunit alpha-1, is a protein that in humans is encoded by the GABRA1 gene. The 1,055-bp GABRA1 clone contained an open reading frame and 260 nucleotides in the 5-prime noncoding region. The 351-amino acid sequence shows 97 % homology with its bovine counterpart. GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified.
Synonyms: ECA4 antibody|EJM antibody|EJM5 antibody|Gaba receptor alpha 1 polypeptide antibody|GABA(A) receptor antibody|GABA(A) receptor subunit alpha 1 antibody|GABA(A) receptor subunit alpha-1 antibody|GABA(A) receptor, alpha 1 antibody|GABRA 1 antibody|GABRA1 antibody|Gamma aminobutyric acid(GABA) A receptor alpha 1 antibody|Gamma aminobutyric acid A receptor alpha 1 antibody|Gamma aminobutyric acid receptor subunit alpha 1 antibody|Gamma-aminobutyric acid receptor subunit alpha-1 antibody|GBRA1_HUMAN antibody - UniProt
- P14867
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