P-Selectin Antikörper (N-Term)
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- Target Alle P-Selectin (SELP) Antikörper anzeigen
- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
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Bindungsspezifität
- AA 49-66, N-Term
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser P-Selectin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Rabbit IgG polyclonal antibody for P-selectin(SELP) detection. Tested with WB, IHC-P in Human.
- Sequenz
- KAYSWNISRK YCQNRYTD
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for P-selectin(SELP) detection. Tested with WB, IHC-P in Human.
Gene Name: selectin P(granule membrane protein 140 kDa, antigen CD62)
Protein Name: P-selectin - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the N-terminus of human CD62P(49-66aa KAYSWNISRKYCQNRYTD).
- Isotyp
- IgG
- Top Product
- Discover our top product SELP Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
- Konservierungsmittel
- Thimerosal (Merthiolate), Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing. - Haltbarkeit
- 12 months
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- Target
- P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
- Andere Bezeichnung
- SELP (SELP Produkte)
- Synonyme
- PSELECT antikoerper, CD62 antikoerper, CD62P antikoerper, GMP140 antikoerper, GRMP antikoerper, LECAM3 antikoerper, PADGEM antikoerper, PSEL antikoerper, GMP-140 antikoerper, Grmp antikoerper, selectin P antikoerper, selectin, platelet antikoerper, Selp antikoerper, SELP antikoerper
- Hintergrund
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P-Selectin, also called CD62, GRMP, GMP140 is a 140-kD adhesion molecule, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes. The P-Selectin gene is mapped on 1q24.2. P-selectin plays an essential role in the initial recruitment of leukocytes(white blood cells) to the site of injury during inflammation. P-selectin is also very important in the recruitment and aggregation of platelets at areas of vascular injury. In quiescent platelet, P-selectin is located on the inner wall of alpha-granules. Sorting nexin-17 interacts with the cytosolic domain of P-selectin and suggested that SNX17 may function in the intracellular trafficking of P-selectin. P-selectin expression was found to be significantly and positively correlated with carotid artery stiffness and wall thickness, and the percentage of P-selectin-positive platelets was significantly higher in patients with carotid plaque.
Synonyms: Antigen CD62 antibody|CD62 antibody|CD62 antigen-like family member P antibody|CD62P antibody|CD62P antigen antibody|FLJ45155 antibody|GMP 140 antibody|GMP-140 antibody|GMP140 antibody|GMRP antibody|Granule membrane protein 140 antibody|Granule membrane protein 140 kDa antibody|Granulocyte membrane protein antibody|GRMP antibody|LECAM 3 antibody|LECAM3 antibody|Leukocyte endothelial cell adhesion molecule 3 antibody|Leukocyte-endothelial cell adhesion molecule 3 antibody|LYAM3_HUMAN antibody|P Selectin antibody|P-selectin antibody|PADGEM antibody|Platelet activation dependent granule external membrane protein antibody|Platelet activation dependent granule-external membrane protein antibody|Platelet alpha granule membrane protein antibody|PSEL antibody|Selectin P(granule membrane protein 140 kDa antigen CD62) antibody|Selectin P(granule membrane protein 140 kDa, antigen CD62) antibody|SELP antibody - UniProt
- P16109
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