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P-Selectin Antikörper (N-Term)

SELP Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3044277
  • Target Alle P-Selectin (SELP) Antikörper anzeigen
    P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
    Bindungsspezifität
    • 16
    • 5
    • 4
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 49-66, N-Term
    Reaktivität
    • 116
    • 39
    • 32
    • 21
    • 13
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 1
    Human
    Wirt
    • 70
    • 62
    • 4
    • 1
    Kaninchen
    Klonalität
    • 75
    • 62
    Polyklonal
    Konjugat
    • 59
    • 18
    • 16
    • 10
    • 6
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser P-Selectin Antikörper ist unkonjugiert
    Applikation
    • 83
    • 76
    • 32
    • 31
    • 30
    • 25
    • 14
    • 13
    • 13
    • 12
    • 10
    • 9
    • 9
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for P-selectin(SELP) detection. Tested with WB, IHC-P in Human.
    Sequenz
    KAYSWNISRK YCQNRYTD
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for P-selectin(SELP) detection. Tested with WB, IHC-P in Human.
    Gene Name: selectin P(granule membrane protein 140 kDa, antigen CD62)
    Protein Name: P-selectin
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human CD62P(49-66aa KAYSWNISRKYCQNRYTD).
    Isotyp
    IgG
    Top Product
    Discover our top product SELP Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Konservierungsmittel
    Thimerosal (Merthiolate), Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Haltbarkeit
    12 months
  • Target
    P-Selectin (SELP) (Selectin P (Granule Membrane Protein 140kDa, Antigen CD62) (SELP))
    Andere Bezeichnung
    SELP (SELP Produkte)
    Synonyme
    PSELECT antikoerper, CD62 antikoerper, CD62P antikoerper, GMP140 antikoerper, GRMP antikoerper, LECAM3 antikoerper, PADGEM antikoerper, PSEL antikoerper, GMP-140 antikoerper, Grmp antikoerper, selectin P antikoerper, selectin, platelet antikoerper, Selp antikoerper, SELP antikoerper
    Hintergrund
    P-Selectin, also called CD62, GRMP, GMP140 is a 140-kD adhesion molecule, expressed at the surface of activated cells, that mediates the interaction of activated endothelial cells or platelets with leukocytes. The P-Selectin gene is mapped on 1q24.2. P-selectin plays an essential role in the initial recruitment of leukocytes(white blood cells) to the site of injury during inflammation. P-selectin is also very important in the recruitment and aggregation of platelets at areas of vascular injury. In quiescent platelet, P-selectin is located on the inner wall of alpha-granules. Sorting nexin-17 interacts with the cytosolic domain of P-selectin and suggested that SNX17 may function in the intracellular trafficking of P-selectin. P-selectin expression was found to be significantly and positively correlated with carotid artery stiffness and wall thickness, and the percentage of P-selectin-positive platelets was significantly higher in patients with carotid plaque.

    Synonyms: Antigen CD62 antibody|CD62 antibody|CD62 antigen-like family member P antibody|CD62P antibody|CD62P antigen antibody|FLJ45155 antibody|GMP 140 antibody|GMP-140 antibody|GMP140 antibody|GMRP antibody|Granule membrane protein 140 antibody|Granule membrane protein 140 kDa antibody|Granulocyte membrane protein antibody|GRMP antibody|LECAM 3 antibody|LECAM3 antibody|Leukocyte endothelial cell adhesion molecule 3 antibody|Leukocyte-endothelial cell adhesion molecule 3 antibody|LYAM3_HUMAN antibody|P Selectin antibody|P-selectin antibody|PADGEM antibody|Platelet activation dependent granule external membrane protein antibody|Platelet activation dependent granule-external membrane protein antibody|Platelet alpha granule membrane protein antibody|PSEL antibody|Selectin P(granule membrane protein 140 kDa antigen CD62) antibody|Selectin P(granule membrane protein 140 kDa, antigen CD62) antibody|SELP antibody
    UniProt
    P16109
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