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VDAC1 Antikörper (Middle Region)

VDAC1 Reaktivität: Human, Ratte, Maus WB, ICC, IHC (p), IHC (fro) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3044167
  • Target Alle VDAC1 Antikörper anzeigen
    VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))
    Bindungsspezifität
    • 15
    • 15
    • 13
    • 7
    • 5
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 163-178, Middle Region
    Reaktivität
    • 99
    • 46
    • 35
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Ratte, Maus
    Wirt
    • 82
    • 25
    Kaninchen
    Klonalität
    • 72
    • 35
    Polyklonal
    Konjugat
    • 46
    • 8
    • 6
    • 6
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser VDAC1 Antikörper ist unkonjugiert
    Applikation
    • 86
    • 52
    • 35
    • 27
    • 27
    • 13
    • 13
    • 9
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Voltage-dependent anion-selective channel protein 1(VDAC1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
    Sequenz
    RVTQSNFAVG YKTDEF
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Voltage-dependent anion-selective channel protein 1(VDAC1) detection. Tested with WB, IHC-P, IHC-F, ICC in Human,Mouse,Rat.
    Gene Name: voltage-dependent anion channel 1
    Protein Name: Voltage-dependent anion-selective channel protein 1(VDAC-1/hVDAC1)
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence in the middle region of human VDAC(163-178aa RVTQSNFAVGYKTDEF), identical to the related rat and mouse sequences.
    Isotyp
    IgG
    Top Product
    Discover our top product VDAC1 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    IHC-F: Concentration: 0.5-1 μg/mL, Tested Species: Rat, Predicted Species: Human, Mouse
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Predicted Species: Rat
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P), IHC(F) and ICC.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Konservierungsmittel
    Thimerosal (Merthiolate), Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Haltbarkeit
    12 months
  • Shen, Chen, Zhang, Du, Bai, Zhang, Jiang, Li, Wang, Zhu: "MicroRNA-27b Regulates Mitochondria Biogenesis in Myocytes." in: PLoS ONE, Vol. 11, Issue 2, pp. e0148532, (2016) (PubMed).

  • Target
    VDAC1 (Voltage-Dependent Anion Channel 1 (VDAC1))
    Andere Bezeichnung
    VDAC1 (VDAC1 Produkte)
    Synonyme
    vdac1 antikoerper, VDAC1 antikoerper, 5076 antikoerper, ARABIDOPSIS THALIANA VOLTAGE DEPENDENT ANION CHANNEL 1 antikoerper, ATVDAC1 antikoerper, T22N4.9 antikoerper, T22N4_9 antikoerper, voltage dependent anion channel 1 antikoerper, PORIN antikoerper, VDAC-1 antikoerper, AL033343 antikoerper, Vdac5 antikoerper, fa13f11 antikoerper, wu:fa13f11 antikoerper, zgc:85830 antikoerper, voltage-dependent anion channel 1 S homeolog antikoerper, voltage-dependent anion channel 1 antikoerper, voltage dependent anion channel 1 antikoerper, vdac1.S antikoerper, vdac1 antikoerper, VDAC1 antikoerper, Vdac1 antikoerper
    Hintergrund
    The voltage-dependent anion channel(VDAC) of the outer mitochondrial membrane is a small, abundant outer membrane pore-forming protein found in the outer membranes of all eukaryotic mitochondria. The VDAC protein is though to form the major pathway for movement of adenine nucleotides through the outer membrane and to be the mitochondrial binding site for hexokinase and glycerol kinase. At low transmembrane voltage, VDAC is open for anions such as phosphate, chloride, and adenine nucleotides. At higher transmembrane voltage, VDAC functions as a selective channel for cations and uncharged molecules. These features make VDAC likely to play a role in mitochondrial energy metabolism. Huizing et al. studied by Northern and Western blot analyses the human tissue distribution of mitochondrial transmembrane metabolite carriers. They found that VDAC1 mRNA has a ubiquitous distribution, with most pronounced expression in heart, liver, and skeletal muscle, whereas the VDAC2 isoform appears to be expressed only in the heart.

    Synonyms: N2441 antibody|OMP2 antibody|POR1 antibody|hVDAC1 antibody|MGC111064 antibody|Mitochondrial Porin antibody|Outer mitochondrial membrane protein porin 1 antibody|Plasmalemmal porin antibody|Porin 31 HL antibody|Porin 31HL antibody|Porin 31HM antibody|VDAC 1 antibody|VDAC antibody|VDAC-1 antibody|VDAC1 antibody|VDAC1_HUMAN antibody|Voltage dependent anion channel 1 antibody|Voltage dependent anion selective channel protein 1 antibody|Voltage-dependent anion-selective channel protein 1 antibody|YNL055C antibody|YNL2441C antibody
    UniProt
    P21796
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