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DCI Antikörper (C-Term)

ECI1 Reaktivität: Human, Ratte WB, IHC (p), ICC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3044153
  • Target Alle DCI (ECI1) Antikörper anzeigen
    DCI (ECI1) (Enoyl-CoA Delta Isomerase 1 (ECI1))
    Bindungsspezifität
    • 11
    • 8
    • 4
    • 3
    • 1
    • 1
    • 1
    • 1
    AA 272-290, C-Term
    Reaktivität
    • 41
    • 21
    • 11
    • 2
    • 1
    Human, Ratte
    Wirt
    • 38
    • 3
    Kaninchen
    Klonalität
    • 41
    Polyklonal
    Konjugat
    • 24
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser DCI Antikörper ist unkonjugiert
    Applikation
    • 34
    • 17
    • 7
    • 6
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Enoyl-CoA delta isomerase 1, mitochondrial(ECI1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    Sequenz
    ADVQNFVSFI SKDSIQKSL
    Kreuzreaktivität (Details)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Enoyl-CoA delta isomerase 1, mitochondrial(ECI1) detection. Tested with WB, IHC-P, ICC in Human,Mouse,Rat.
    Gene Name: enoyl-CoA delta isomerase 1
    Protein Name: Enoyl-CoA delta isomerase 1, mitochondrial
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human DCI(272-290aa ADVQNFVSFISKDSIQKSL), different from the related mouse sequence by two amino acids and from the related rat sequence by three amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product ECI1 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Konservierungsmittel
    Thimerosal (Merthiolate), Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Haltbarkeit
    12 months
  • Target
    DCI (ECI1) (Enoyl-CoA Delta Isomerase 1 (ECI1))
    Andere Bezeichnung
    ECI1 (ECI1 Produkte)
    Synonyme
    DCI antikoerper, Dci antikoerper, eci antikoerper, enoyl-CoA delta isomerase 1 antikoerper, enoyl-Coenzyme A delta isomerase 1 antikoerper, ECI1 antikoerper, Eci1 antikoerper
    Hintergrund
    ECI1/DCI(Dodecenoyl-CoA Delta Isomerase), also known as 3,2-trans-enoyl-CoA isomerase, is an enzyme that catalyzes the conversion of cis-or trans-double bonds of fatty acids at gamma-carbon(position 3) to trans double bonds at beta-carbon(position 2). It plays a particularly important role in the metabolism of unsaturated fatty acids. All classes of enoyl-CoA isomerases belong to a family of enzymes, the hydratase/isomerase or crotonase superfamily, and when examined with x-ray crystallography, exhibit a common structural feature of the family, the N-terminal core with a spiral fold composed of four turns, each turn consisting of two beta-sheets and one alpha-helix. Dodecenoyl-CoA Delta Isomerase is involved in the beta-oxidation, one of the most frequently used pathways in fatty acid degradation, of unsaturated fatty acids with double bonds at odd-numbered carbon positions. It does so by shifting the position of the double bonds in the acyl-CoA intermediates and converting 3-cis or trans-enoyl-CoA to 2-trans-enoyl-CoA.

    Synonyms: 3,2 trans enoyl Coenzyme A isomerase antibody|Acetylene allene isomerase antibody|D3,D2 enoyl CoA isomerase antibody|DCI antibody|DCI protein antibody|Delta(3),Delta(2) enoyl CoA isomerase antibody|Delta3, delta2 enoyl CoA isomerase antibody|Dodecenoyl CoA delta Isomerase antibody|Dodecenoyl CoA isomerase antibody|Dodecenoyl Coenzyme A delta isomerase antibody|Dodecenoyl Coenzyme A delta isomerase(3,2 trans enoyl Coenzyme A isomerase) antibody|Dodecenoyl Coenzyme A delta isomerase 3,2 trans enoyl Coenzyme A isomerase, isoform CRA a antibody
    UniProt
    P42126
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