Dual Specificity Phosphatase 3 (DUSP3) (AA 155-171), (C-Term) Antikörper

Produktnummer ABIN3044152

Produktdetails

Target: Dual Specificity Phosphatase 3 (DUSP3)

Bindungsspezifität: AA 155-171, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Dual specificity protein phosphatase 3(DUSP3) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: RQNREIGPND GFLAQLC

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Dual specificity protein phosphatase 3(DUSP3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: dual specificity phosphatase 3
Protein Name: Dual specificity protein phosphatase 3

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human DUSP3(155-171aa RQNREIGPNDGFLAQLC), identical to the related rat and mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: Dual Specificity Phosphatase 3 (DUSP3)

Andere Bezeichnung: DUSP3 (DUSP3 Produkte)

Synonyme: dusp3 antikoerper, si:bz18k17.3 antikoerper, si:rp71-18k17.3 antikoerper, VHR antikoerper, RGD1560049 antikoerper, 2210015O03Rik antikoerper, 5031436O03Rik antikoerper, T-DSP11 antikoerper, dual specificity phosphatase 3 antikoerper, dual specificity phosphatase 3b antikoerper, dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related) antikoerper, DUSP3 antikoerper, dusp3b antikoerper, Dusp3 antikoerper

Substanzklasse: Viral Protein

Hintergrund: DUSP3(Dual-specificity phosphatase 3), also called VHR, is a member of the dual specificity protein phosphatase subfamily. DUSPs constitute a large heterogeneous subgroup of the type I cysteine-based protein-tyrosine phosphatase superfamily. DUSPs are characterized by their ability to dephosphorylate both tyrosine and serine/threonine residues. DUSP3 contains the consensus DUSP C-terminal catalytic domain but lacks the N-terminal CH2 domain found in the MKP(mitogen-activated protein kinase phosphatase) class of DUSPs. The DUSP3 gene is mapped on 17q21.31. Confocal microscopy demonstrated that phosphorylated VHR accumulated at the immune synapse between the T cell and the antigen-presenting cell in the presence of antigen. Tyrosine phosphorylation of VHR affects protein-protein interaction, subcellular location, or substrate targeting, given that tyr138 is located on the opposite side of the VHR catalytic center.

Synonyms: Dual specificity phosphatase 3 antibody|Dual specificity protein phosphatase 3 antibody|Dual specificity protein phosphatase VHR antibody|DUS3_HUMAN antibody|DUSP3 antibody|Serine/threonine specific protein phosphatase antibody|Vaccinia H1-related phosphatase antibody|Vaccinia virus phosphatase VH1 related antibody|VHR antibody

UniProt: P51452

Pathways: Neurotrophin Signalübertragung, Activation of Innate immune Response, Toll-Like Receptors Cascades