CSF3R Antikörper (Middle Region)

Produktnummer ABIN3044116

Produktdetails anti-CSF3R Antikörper

Target: CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))

Bindungsspezifität: AA 254-271, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CSF3R Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Granulocyte colony-stimulating factor receptor(CSF3R) detection. Tested with WB in Human.

Sequenz: EPWQPGLHIN QKCELRHK

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Granulocyte colony-stimulating factor receptor(CSF3R) detection. Tested with WB in Human.
Gene Name: Colony stimulating factor 3 receptor(granulocyte)
Protein Name: Granulocyte colony-stimulating factor receptor

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human GCSF Receptor(254-271aa EPWQPGLHINQKCELRHK).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for CSF3R is approximately 5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu CSF3R

Target: CSF3R (Colony Stimulating Factor 3 Receptor (Granulocyte) (CSF3R))

Andere Bezeichnung: CSF3R (CSF3R Produkte)

Synonyme: CD114 antikoerper, GCSFR antikoerper, Cd114 antikoerper, Csfgr antikoerper, G-CSF-R antikoerper, G-CSFR antikoerper, CSF3R antikoerper, gcsfr antikoerper, cd114 antikoerper, colony stimulating factor 3 receptor antikoerper, colony stimulating factor 3 receptor (granulocyte) antikoerper, colony stimulating factor 3 receptor L homeolog antikoerper, granulocyte colony-stimulating factor receptor antikoerper, CSF3R antikoerper, Csf3r antikoerper, csf3r antikoerper, csf3r.L antikoerper, LOC100433338 antikoerper

Hintergrund: CSF3R(Colony-Stimulating Factor 3 Receptor, Granulocyte) also known as GCSFR or CD114((Cluster of Differentiation 114) is a protein that in humans is encoded by the CSF3R gene. G-CSF-R is a cell-surface receptor for the granulocyte colony-stimulating factor(G-CSF). The G-CSF receptors belongs to a family of cytokine receptors known as the hematopoietin receptor family. The CSF3R gene consists of 17 exons. By in situ hybridization using human CSF3R cDNA as a probe, Inazawa et al.(1991) localized the gene to 1p35-p34.3. The G-CSF-R is a transmembrane receptor that consists of an extracellular ligand-binding portion, a transmembrane domain, and the cytoplasmic portion that is responsible for signal transduction. GCSF-R ligand-binding is associated with dimerization of the receptor and signal transduction through proteins including Jak, Lyn, STAT, and Erk1/2. Dong et al.(2001) reported that the C terminus of CSF3R is required for SHP1 downregulation of CSF3-induced STAT activation. The authors proposed that this mechanism inhibits cell proliferation and survival in response to CSF3.

Synonyms: CD 114 antibody|CD114 antibody|CD114 antigen antibody|Colony stimulating factor 3 receptor(granulocyte) antibody|Colony stimulating factor 3 receptor antibody|CSF 3R antibody|CSF3R antibody|CSF3R_HUMAN antibody|Csfgr antibody|G CSF R antibody|G-CSF receptor antibody|G-CSF-R antibody|GCSFR antibody|Granulocyte colony stimulating factor receptor antibody|Granulocyte colony stimulating factor receptor precursor antibody|Granulocyte colony-stimulating factor receptor antibody|OTTHUMP00000009703 antibody|OTTHUMP00000009704 antibody|OTTHUMP00000009705 antibody

UniProt: Q99062