TNFRSF1B Antikörper (C-Term)
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- Target Alle TNFRSF1B Antikörper anzeigen
- TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
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Bindungsspezifität
- AA 296-324, C-Term
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Reaktivität
- Maus, Ratte
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser TNFRSF1B Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) detection. Tested with WB, IHC-P in Mouse,Rat.
- Sequenz
- QRDAKVPHVP DEKSQDAVGL EQQHLLTTA
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 1B (TNFRSF1B) detection. Tested with WB, IHC-P in Mouse,Rat.
Gene Name: tumor necrosis factor receptor superfamily, member 1B
Protein Name: Tumor necrosis factor receptor superfamily member 1B - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- A synthetic peptide corresponding to a sequence at the C-terminus of mouse TNF Receptor II (296-324aa QRDAKVPHVPDEKSQDAVGLEQQHLLTTA), different from the related human sequence by eleven amino acids, and from the related rat sequence by six amino acids.
- Isotyp
- IgG
- Top Product
- Discover our top product TNFRSF1B Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therapy Using the Bifidobacterium-Mediated Recombinant HSV-1 Thymidine Kinase and Ganciclovir." in: International journal of molecular sciences, Vol. 17, Issue 6, (2017) (PubMed).
: "Powerful inner/outer controlled multi-target magnetic nanoparticle drug carrier prepared by liquid photo-immobilization." in: Scientific reports, Vol. 4, pp. 4990, (2015) (PubMed).
: "
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Intravenous Administration Is an Effective and Safe Route for Cancer Gene Therapy Using the Bifidobacterium-Mediated Recombinant HSV-1 Thymidine Kinase and Ganciclovir." in: International journal of molecular sciences, Vol. 17, Issue 6, (2017) (PubMed).
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- Target
- TNFRSF1B (Tumor Necrosis Factor Receptor Superfamily, Member 1B (TNFRSF1B))
- Andere Bezeichnung
- TNFRSF1B (TNFRSF1B Produkte)
- Synonyme
- CD120b antikoerper, TBPII antikoerper, TNF-R-II antikoerper, TNF-R75 antikoerper, TNFBR antikoerper, TNFR1B antikoerper, TNFR2 antikoerper, TNFR80 antikoerper, p75 antikoerper, p75TNFR antikoerper, TNF-RII/TNFRSF1B antikoerper, TNFR-II antikoerper, TNFRSF1B antikoerper, TNF-R2 antikoerper, TNF-alphaR2 antikoerper, TNFRII antikoerper, TNFalpha-R2 antikoerper, Tnfr-1 antikoerper, Tnfr2 antikoerper, rank antikoerper, zgc:163064 antikoerper, TNF receptor superfamily member 1B antikoerper, tumor necrosis factor receptor superfamily, member 1b antikoerper, tumor necrosis factor receptor superfamily, member 1B antikoerper, TNFRSF1B antikoerper, Tnfrsf1b antikoerper, tnfrsf1b antikoerper
- Hintergrund
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Tumor necrosis factor receptor 2 (TNFR2) is one of receptors of TNF. TNF has proinflammatory and immunosuppressive properties that may segregate at the level of the 2 TNF receptors (TNFRs), TNFR1 and TNFR2. The genes for TNFR1, a 55- kDa protein, and TNFR2, a 70- kDa protein, have been mapped to human chromosomes 12 (12pter-cen) and 1 (1pter-p32), respectively. TNFR2 was induced on glomerular endothelial cells of nephritic kidneys, and TNFR2 expression on intrinsic cells, but not leukocytes, was essential for glomerulonephritis and glomerular complement deposition. TNFR1 promotes systemic immune responses and renal T cell death, while intrinsic cell TNFR2 plays a critical role in complement-dependent tissue injury. Therefore, therapeutic blockade specifically of TNFR2 may be a promising strategy in the treatment of immune-mediated glomerulonephritis.
Synonyms: CD 120b antibody|CD120b antibody|CD120b antigen antibody|Etanercept antibody|p75 antibody| p75TNFR antibody|p80 TNF alpha receptor antibody|p80 TNF-alpha receptor antibody|TBP-2 antibody|TBP2 antibody|TBPII antibody|TNF R II antibody|TNF R2 antibody|TNF R75 antibody| TNF-R2 antibody|TNF-RII antibody|TNFBR antibody|TNFR 2 antibody|TNFR-II antibody|TNFR2 antibody|TNFR75 antibody|TNFR80 antibody|TNFRII antibody|TNFRSF 1B antibody|TNFRSF1B antibody|TNR1B antibody|TNR1B_HUMAN antibody|Tumor necrosis factor beta receptor antibody| Tumor necrosis factor binding protein 2 antibody|Tumor necrosis factor receptor 2 antibody| Tumor necrosis factor receptor superfamily member 1B precursor antibody|Tumor necrosis factor receptor type II antibody|Tumor necrosis factor-binding protein 2 antibody - Gen-ID
- 21938
- UniProt
- P25119
- Pathways
- NF-kappaB Signalweg, Apoptose, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Ubiquitin Proteasome Pathway
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