Laminin Antikörper
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- Target Alle Laminin (LN) Antikörper anzeigen
- Laminin (LN)
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser Laminin Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)
- Verwendungszweck
- Rabbit IgG polyclonal antibody for Laminin subunit gamma-1&Laminin subunit gamma-2&Laminin subunit gamma-3(LAMC1&LAMC2&LAMC3) detection. Tested with WB, IHC-P, ICC in Human.
- Sequenz
- DLNKLNEIEG TLNKAKDEMK ,MSELEERARQ QRGHLHLLET ,LQRKLSLLEQ ESQQQELQIQ
- Kreuzreaktivität (Details)
- No cross reactivity with other proteins.
- Produktmerkmale
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Rabbit IgG polyclonal antibody for Laminin subunit gamma-1&Laminin subunit gamma-2&Laminin subunit gamma-3(LAMC1&LAMC2&LAMC3) detection. Tested with WB, IHC-P, ICC in Human.
Gene Name: laminin, gamma 1 (formerly LAMB2)&laminin, gamma 2&laminin, gamma 3
Protein Name: Laminin subunit gamma-1&Laminin subunit gamma-2&Laminin subunit gamma-3 - Aufreinigung
- Immunogen affinity purified.
- Immunogen
- Peptide mixture of laminin gamma1,2,3(DLNKLNEIEGTLNKAKDEMK, MSELEERARQQRGHLHLLET, LQRKLSLLEQESQQQELQIQ). Laminin gamma has only three subtypes of antibody to gamma1-3 reactive with all isoforms of laminin.
- Isotyp
- IgG
- Top Product
- Discover our top product LN Primärantikörper
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- Applikationshinweise
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WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Laminin is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ICC: Concentration: 0.5-1 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users. - Kommentare
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Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P) and ICC.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Lyophilized
- Rekonstitution
- Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
- Konzentration
- 500 μg/mL
- Buffer
- Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freezing and thawing.
- Lagerung
- 4 °C/-20 °C
- Informationen zur Lagerung
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At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
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Remarkable preservation of Ca(2+) homeostasis and inhibition of apoptosis contribute to anti-muscle atrophy effect in hibernating Daurian ground squirrels." in: Scientific reports, Vol. 6, pp. 27020, (2018) (PubMed).
: "Engineering blood vessels through micropatterned co-culture of vascular endothelial and smooth muscle cells on bilayered electrospun fibrous mats with pDNA inoculation." in: Acta biomaterialia, Vol. 11, pp. 114-25, (2014) (PubMed).
: "Effects of transforming growth factor-?2 on myocilin expression and secretion in human primary cultured trabecular meshwork cells." in: International journal of clinical and experimental pathology, Vol. 7, Issue 8, pp. 4827-36, (2014) (PubMed).
: "Comparison of morphology and biocompatibility of acellular nerve scaffolds processed by different chemical methods." in: Journal of materials science. Materials in medicine, Vol. 25, Issue 5, pp. 1283-91, (2014) (PubMed).
: "Three dimensional chitosan scaffolds influence the extra cellular matrix expression in Schwann cells." in: Materials science & engineering. C, Materials for biological applications, Vol. 42, pp. 474-8, (2014) (PubMed).
: "Highly effective ex vivo gene manipulation to study kidney development using self-complementary adenoassociated viruses." in: TheScientificWorldJournal, Vol. 2014, pp. 682189, (2014) (PubMed).
: "Pulmonary endoderm, second heart field and the morphogenesis of distal outflow tract in mouse embryonic heart." in: Development, growth & differentiation, Vol. 56, Issue 4, pp. 276-92, (2014) (PubMed).
: "Promoted regeneration of mature blood vessels by electrospun fibers with loaded multiple pDNA-calcium phosphate nanoparticles." in: European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fu?r Pharmazeutische Verfahrenstechnik e.V, Vol. 85, Issue 3 Pt A, pp. 699-710, (2013) (PubMed).
: "Puerarin, isolated from Pueraria lobata (Willd.), protects against hepatotoxicity via specific inhibition of the TGF-?1/Smad signaling pathway, thereby leading to anti-fibrotic effect." in: Phytomedicine : international journal of phytotherapy and phytopharmacology, Vol. 20, Issue 13, pp. 1172-9, (2013) (PubMed).
: "In vitro culture of tumour-derived hepatocytes in decellularised whole-liver biological scaffolds." in: Digestion, Vol. 87, Issue 3, pp. 189-95, (2013) (PubMed).
: "Anti-fibrotic effects of puerarin on CCl4-induced hepatic fibrosis in rats possibly through the regulation of PPAR-? expression and inhibition of PI3K/Akt pathway." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 56, pp. 436-42, (2013) (PubMed).
: "Transcriptome sequencing reveals differences between primary and secondary hair follicle-derived dermal papilla cells of the Cashmere goat (Capra hircus)." in: PLoS ONE, Vol. 8, Issue 9, pp. e76282, (2013) (PubMed).
: "Multiple release of polyplexes of plasmids VEGF and bFGF from electrospun fibrous scaffolds towards regeneration of mature blood vessels." in: Acta biomaterialia, Vol. 8, Issue 7, pp. 2659-69, (2012) (PubMed).
: "Effects of in vitro cultivated Calculus Bovis compound on pulmonary lesions in rabbits with schistosomiasis." in: World journal of gastroenterology, Vol. 16, Issue 6, pp. 749-54, (2010) (PubMed).
: "Microplasmin degrades fibronectin and laminin at vitreoretinal interface and outer retina during enzymatic vitrectomy." in: Current eye research, Vol. 34, Issue 12, pp. 1057-64, (2009) (PubMed).
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Remarkable preservation of Ca(2+) homeostasis and inhibition of apoptosis contribute to anti-muscle atrophy effect in hibernating Daurian ground squirrels." in: Scientific reports, Vol. 6, pp. 27020, (2018) (PubMed).
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- Target
- Laminin (LN)
- Andere Bezeichnung
- Laminin (LN Produkte)
- Synonyme
- LAMC1 antikoerper, laminin antikoerper, laminin, beta 2 (laminin S) antikoerper, LAMB2 antikoerper
- Hintergrund
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Laminins are major proteins in the basal lamina (one of the layers of the basement membrane), a protein network foundation for most cells and organs. Laminins form independent networks and are associated with type IV collagen networks via entactin, fibronectin, and perlecan. They are important and biologically active parts of the basal lamina, influencing cell differentiation, migration, and adhesion, as well as phenotype and survival. Laminins are trimeric proteins that contain an α-chain, a β-chain, and a γ-chain, found in five, four, and three genetic variants, respectively. Laminins critically contribute to cell attachment and differentiation, cell shape and movement, maintenance of tissue phenotype, and promotion of tissue survival.
Synonyms: LAMB 2 antibody|LAMB2 antibody|LAMC 1 antibody|LAMC1 antibody|Laminin B2 chain antibody|Laminin gamma 1 antibody|Laminin gamma 1 chain antibody|MGC87297 antibody|3918 antibody|B2T antibody|BM600 antibody|Cell-scattering factor 140 kDa subunit antibody|CSF 140 kDa subunit antibody|CSF antibody|EBR2 antibody|EBR2A antibody|Epiligrin subunit gamma antibody|Kalinin subunit gamma antibody|Kalinin/nicein/epiligrin 100 kDa subunit antibody|Ladsin 140 kDa subunit antibody|LAMB2T antibody|LAMC2 antibody|LAMC2_HUMAN antibody|Laminin 5 gamma 2 subunit antibody|Laminin B2t chain antibody|Laminin gamma 2 antibody|laminin gamma 2 chain antibody|Laminin subunit gamma-2 antibody|Laminin-5 subunit gamma antibody|LAMNB2 antibody|Large adhesive scatter factor 140 kDa subunit antibody|MGC138491 antibody|MGC141938 antibody|Nicein subunit gamma antibody|NICEIN-100KDA antibody|LAMA 1 antibody|LAMA antibody|LAMA1 antibody|LAMB1 antibody|Lamc3 antibody|LAMC3_HUMAN antibody|Laminin A chain antibody|Laminin alpha 1 antibody|Laminin alpha 1 chain antibody|Laminin B1 chain antibody|Laminin subunit beta 1 antibody|Laminin subunit gamma-3 antibody|Laminin-12 subunit gamma antibody|Laminin-14 subunit gamma antibody|Laminin-15 subunit gamma antibody - Gen-ID
- 3915, 3918, 10319
- UniProt
- P11047, Q13753, Q9Y6N6
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