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IRF5 Antikörper (C-Term)

IRF5 Reaktivität: Human, Maus, Ratte WB, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3043861
  • Target Alle IRF5 Antikörper anzeigen
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    Bindungsspezifität
    • 9
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 442-472, C-Term
    Reaktivität
    • 72
    • 48
    • 22
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    Human, Maus, Ratte
    Wirt
    • 73
    • 10
    • 1
    • 1
    Kaninchen
    Klonalität
    • 65
    • 20
    Polyklonal
    Konjugat
    • 53
    • 6
    • 5
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    Dieser IRF5 Antikörper ist unkonjugiert
    Applikation
    • 48
    • 30
    • 12
    • 11
    • 10
    • 6
    • 6
    • 6
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Interferon regulatory factor 5(IRF5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Sequenz
    RLQISNPDLK DRMVEQFKEL HHIWQSQQRL Q
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Interferon regulatory factor 5(IRF5) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: interferon regulatory factor 5
    Protein Name: Interferon regulatory factor 5
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human IRF5 (442-472aa RLQISNPDLKDRMVEQFKELHHIWQSQQRLQ), different from the related mouse sequence by three amino acids.
    Isotyp
    IgG
    Top Product
    Discover our top product IRF5 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    IRF5 (Interferon Regulatory Factor 5 (IRF5))
    Andere Bezeichnung
    IRF5 (IRF5 Produkte)
    Synonyme
    IRF5 antikoerper, irf5 antikoerper, SLEB10 antikoerper, AW491843 antikoerper, mirf5 antikoerper, im:7155364 antikoerper, zgc:76986 antikoerper, interferon regulatory factor 5 antikoerper, interferon regulatory factor 5 L homeolog antikoerper, IRF5 antikoerper, irf5 antikoerper, Irf5 antikoerper, irf5.L antikoerper
    Hintergrund
    Interferon regulatory factor 5, also called IRF5 or SLEB10, is a protein that in humans is encoded by the IRF5 gene. IRF5 gene is mapped to 7q32.1. This gene encodes a member of the interferon regulatory factor (IRF) family, a group of transcription factors with diverse roles, including virus-mediated activation of interferon, and modulation of cell growth, differentiation, apoptosis, and immune system activity. Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats. Multiple transcript variants encoding different isoforms have been found for this gene, and a 30-nt indel polymorphism (SNP rs60344245) can result in loss of a 10-aa segment. This gene is a transcription factor involved in the induction of interferons IFNA and INFB and inflammatory cytokines upon virus infection.

    Synonyms: Interferon regulatory factor 5 antibody|Interferon regulatory factor 5 bone marrow variant antibody|IRF 5 antibody|IRF-5 antibody|Irf5 antibody|IRF5_HUMAN antibody|SLEB10 antibody
    Gen-ID
    3663
    UniProt
    Q13568
    Pathways
    TLR Signalweg, Autophagie
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