CACNA1D Antikörper (AA 1-180)

Produktnummer ABIN3043768

Produktdetails anti-CACNA1D Antikörper

Target: CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))

Bindungsspezifität: AA 1-180

Reaktivität: Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1D Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Voltage-dependent L-type calcium channel subunit alpha-1D(CACNA1D) detection. Tested with WB in Human,Mouse,Rat.

Kreuzreaktivität (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Voltage-dependent L-type calcium channel subunit alpha-1D(CACNA1D) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: calcium channel, voltage-dependent, L type, alpha 1D subunit
Protein Name: Voltage-dependent L-type calcium channel subunit alpha-1D

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human CaV1.3 recombinant protein (Position: M1-I180). Human CaV1.3 shares 99% and 98%amino acid (aa) sequence identity with mouse and rat CaV1.3, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, The detection limit for CaV1.3 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-CACNA1D Antikörper (ABIN3043768)

Guo, Cui, Jiang, Zhang, Jiang: "Proteomics of acute heart failure in a rat post-myocardial infarction model." in: Molecular medicine reports, Vol. 16, Issue 2, pp. 1946-1956, (2018) (PubMed).

Details zu CACNA1D

Target: CACNA1D (Calcium Channel, Voltage-Dependent, L Type, alpha 1D Subunit (CACNA1D))

Andere Bezeichnung: CACNA1D (CACNA1D Produkte)

Synonyme: cacna1d antikoerper, cav1.3a antikoerper, isl antikoerper, si:dz136d19.3 antikoerper, si:dz223c6.1 antikoerper, ca(v)1.3 antikoerper, cav1.3 antikoerper, CACH3 antikoerper, CACN4 antikoerper, CACNL1A2 antikoerper, CCHL1A2 antikoerper, Cav1.3 antikoerper, SANDD antikoerper, 8430418G19Rik antikoerper, C79217 antikoerper, Cacnl1a2 antikoerper, Cchl1a antikoerper, Cchl1a2 antikoerper, D-LTCC antikoerper, calcium channel, voltage-dependent, L type, alpha 1D subunit, a antikoerper, calcium voltage-gated channel subunit alpha1 D antikoerper, calcium channel, voltage-dependent, L type, alpha 1D subunit antikoerper, calcium channel, voltage-dependent, L type, alpha 1D subunit L homeolog antikoerper, cacna1da antikoerper, CACNA1D antikoerper, cacna1d antikoerper, cacna1d.L antikoerper, Cacna1d antikoerper

Hintergrund: CACNA1D is also known as PASNA, SANDD or Cav1.3. Voltage-dependent calcium channels mediate the entry of calcium ions into excitable cells, and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, and gene expression. Calcium channels are multisubunit complexes composed of alpha-1, beta, alpha-2/delta, and gamma subunits. The channel activity is directed by the pore-forming alpha-1 subunit, whereas the others act as auxiliary subunits regulating this activity. The distinctive properties of the calcium channel types are related primarily to the expression of a variety of alpha-1 isoforms, namely alpha-1A, B, C, D, E, and S. This gene encodes the alpha-1D subunit. Several transcript variants encoding different isoforms have been found for this gene.

Synonyms: alpha-1 polypeptide antibody|CAC1D_HUMAN antibody|CACH3 antibody|CACN4 antibody|CACNA 1D antibody|CACNA1D antibody|CACNL1A2 antibody|Calcium channel antibody|Calcium channel L type alpha 1 polypeptide isoform 2 antibody|Calcium channel neuroendocrine/brain type alpha 1 subunit antibody|Calcium channel voltage dependent L type alpha 1 antibody|Calcium channel voltage dependent L type alpha 1D subunit antibody|Cav1.3 antibody|CCHL1A2 antibody|L type antibody|PASNA antibody|SANDD antibody|Voltage dependent L type calcium channel subunit alpha 1D antibody|Voltage gated calcium channel alpha 1 subunit antibody|Voltage gated calcium channel alpha subunit Cav1.3 antibody|Voltage gated calcium channel subunit alpha Cav1.3 antibody|Voltage-dependent L-type calcium channel subunit alpha-1D antibody|Voltage-gated calcium channel subunit alpha Cav1.3 antibody

Gen-ID: 776

UniProt: Q01668

Pathways: Sensory Perception of Sound