PDGFB Antikörper (AA 82-190)

Produktnummer ABIN3043599

Produktdetails anti-PDGFB Antikörper

Target: PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))

Bindungsspezifität: AA 82-190

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDGFB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Platelet-derived growth factor subunit B(PDGFB) detection. Tested with WB in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Platelet-derived growth factor subunit B(PDGFB) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: platelet-derived growth factor beta polypeptide
Protein Name: Platelet-derived growth factor subunit B

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human PDGF beta recombinant protein (Position: S82-T190). Human PDGF beta shares 89% amino acid (aa) sequence identity with both mouse and rat PDGF beta.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for PDGF beta is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-PDGFB Antikörper (ABIN3043599)

Hong, Hong, Chen, Wang, Hong: "Investigation of the protective effect of erythropoietin on spinal cord injury in rats." in: Experimental and therapeutic medicine, Vol. 2, Issue 5, pp. 837-841, (2012) (PubMed).

Zhao, Wang, Liu, Sun, Kazuhiro: "Protective effects of glutamine in a rat model of endotoxemia." in: Molecular medicine reports, Vol. 6, Issue 4, pp. 739-44, (2012) (PubMed).

Details zu PDGFB

Target: PDGFB (Platelet Derived Growth Factor Subunit B (PDGFB))

Andere Bezeichnung: PDGFB (PDGFB Produkte)

Synonyme: PDGF-2 antikoerper, PDGF2 antikoerper, SIS antikoerper, SSV antikoerper, c-sis antikoerper, pdgf2 antikoerper, sis antikoerper, si:ch211-79m20.1 antikoerper, si:dkey-261d11.1 antikoerper, PDGF-B antikoerper, Sis antikoerper, platelet derived growth factor subunit B antikoerper, platelet-derived growth factor beta polypeptide antikoerper, platelet derived growth factor subunit B S homeolog antikoerper, platelet-derived growth factor beta polypeptide a antikoerper, platelet derived growth factor, B polypeptide antikoerper, PDGFB antikoerper, pdgfb.S antikoerper, pdgfba antikoerper, Pdgfb antikoerper

Hintergrund: Platelet-derived growth factor subunit B is a protein that in humans is encoded by the PDGFB gene. The protein encoded by this gene is a member of the platelet-derived growth factor family. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. This gene is mapped to 22q13.1. Growth factor plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. This gene plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFA.

Synonyms: Becaplermin antibody|c sis antibody|FLJ12858 antibody|Oncogene SIS antibody|PDGF 2 antibody|PDGF B antibody|PDGF B chain antibody|PDGF subunit B antibody|PDGF-2 antibody|PDGF2 antibody|Pdgfb antibody|PDGFB_HUMAN antibody|Platelet derived growth factor 2 antibody|Platelet derived growth factor B chain antibody|Platelet derived growth factor beta antibody|Platelet derived growth factor beta polypeptide (oncogene SIS) antibody|Platelet derived growth factor beta polypeptide (simian sarcoma viral (v sis) oncogene homolog) antibody|Platelet derived growth factor beta polypeptide antibody|Platelet-derived growth factor B chain antibody|Platelet-derived growth factor beta polypeptide antibody|Platelet-derived growth factor subunit B antibody|Proto-oncogene c-Sis antibody|Simian sarcoma viral (v sis) oncogene homolog antibody|SIS antibody|SSV antibody|v sis platelet derived growth factor beta polypeptide antibody

Gen-ID: 5155

UniProt: P01127

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Carbohydrate Metabolic Process, Smooth Muscle Cell Migration, Platelet-derived growth Factor Receptor Signaling