RAD51C Antikörper (Middle Region)

Produktnummer ABIN3043564

Produktdetails anti-RAD51C Antikörper

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Bindungsspezifität: AA 177-207, Middle Region

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAD51C Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for DNA repair protein RAD51 homolog 3(RAD51C) detection. Tested with WB in Human.

Sequenz: IQHLQLIAEK HKGEEHRKAL EDFTLDNILS H

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for DNA repair protein RAD51 homolog 3(RAD51C) detection. Tested with WB in Human.
Gene Name: RAD51 paralog C
Protein Name: DNA repair protein RAD51 homolog 3

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence in the middle region of human Rad51C (177-207aa IQHLQLIAEKHKGEEHRKALEDFTLDNILSH), different from the related mouse sequence by eight amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu RAD51C

Target: RAD51C (DNA Repair Protein RAD51 Homolog 3 (RAD51C))

Andere Bezeichnung: RAD51C (RAD51C Produkte)

Synonyme: RGD1563765 antikoerper, CG2412 antikoerper, Dm CG2412 antikoerper, Dmel\\CG2412 antikoerper, zgc:101596 antikoerper, RAD51C antikoerper, Rad51c antikoerper, ATRAD51C antikoerper, F4L23.21 antikoerper, RAS associated with diabetes protein 51C antikoerper, R51H3 antikoerper, Rad51l2 antikoerper, BROVCA3 antikoerper, FANCO antikoerper, RAD51L2 antikoerper, RAD51 paralog C antikoerper, Rad51 recombinase D antikoerper, Rad51 DNA recombinase 3 antikoerper, RAD51C protein antikoerper, RAD51 homolog C antikoerper, RAS associated with diabetes protein 51C antikoerper, RAD51C antikoerper, Rad51c antikoerper, Rad51D antikoerper, rad51c antikoerper

Hintergrund: RAD51 homolog C (S. cerevisiae), also known as RAD51C, is a protein which in humans is encoded by the RAD51C gene. This gene is a member of the RAD51 family of related genes, which encode strand-transfer proteins thought to be involved in recombinational repair of damaged DNA and in meiotic recombination. Ana this gene product interacts with two other DNA repair proteins, encoded by RAD51B and XRCC3, but not with itself. The protein copurifies with XRCC3 protein in a complex, reflecting their endogenous association and suggesting a cooperative role during recombinational repair. This gene is one of four localized to a region of chromosome 17q23 where amplification occurs frequently in breast tumors. Overexpression of the four genes during amplification has been observed and suggests a possible role in tumor progression. Alternative splicing has been observed for this gene and two variants encoding different isoforms have been identified.

Synonyms: DNA repair protein RAD51 homolog 3 antibody|MGC104277 antibody|R51H3 antibody|RA51C_HUMAN antibody|Rad 51C antibody|RAD51 homolog C (S. cerevisiae) antibody|Rad51 homolog c (S. cerevisiae), isoform CRA_b antibody|RAD51 homolog C antibody|RAD51 like protein 2 antibody|RAD51, S. cerevisiae, homolog of, C antibody|RAD51-like protein 2 antibody|RAD51C antibody|RAD51C protein antibody|RAD51L2 antibody|RAD51L2/RAD51C protein antibody|RGD1563765 antibody|Yeast RAD51 homolog 3 antibody

Gen-ID: 5889

UniProt: O43502

Pathways: DNA Reparatur