TRPM8 Antikörper (C-Term)

Produktnummer ABIN3043495

Produktdetails anti-TRPM8 Antikörper

Target: TRPM8 (Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8))

Bindungsspezifität: AA 1068-1104, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TRPM8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Transient receptor potential cation channel subfamily M member 8(TRPM8) detection. Tested with WB in Human.

Sequenz: NTKANDTSEE MRHRFRQLDT KLNDLKGLLK EIANKIK

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Transient receptor potential cation channel subfamily M member 8(TRPM8) detection. Tested with WB in Human.
Gene Name: transient receptor potential cation channel, subfamily M, member 8
Protein Name: Transient receptor potential cation channel subfamily M member 8

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human TRPM8 (1068-1104aa NTKANDTSEEMRHRFRQLDTKLNDLKGLLKEIANKIK), different from the related mouse sequence by four amino acids, and from the related rat sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu TRPM8

Target: TRPM8 (Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8))

Andere Bezeichnung: TRPM8 (TRPM8 Produkte)

Synonyme: TRPM8 antikoerper, trpp8 antikoerper, ltrpc6 antikoerper, trpm8b antikoerper, LTRPC6 antikoerper, TRPP8 antikoerper, CMR1 antikoerper, LTrpC-6 antikoerper, Trp-p8 antikoerper, transient receptor potential cation channel subfamily M member 8 antikoerper, transient receptor potential cation channel subfamily M member 8b L homeolog antikoerper, transient receptor potential cation channel, subfamily M, member 8 antikoerper, TRPM8 antikoerper, trpm8b.L antikoerper, Trpm8 antikoerper

Hintergrund: Transient receptor potential cation channel subfamily M member 8 (TRPM8), also known as the cold and menthol receptor 1 (CMR1), is a protein that in humans is encoded by the TRPM8 gene. TRPM8 is an ion channel, upon activation it allows the entry of Na+ (sodium) and Ca2+ (calcium) ions to the cell that leads to depolarization and the generation of an action potential. The signal is conducted from primary afferents (type C- and A-delta) eventually leading to the sensation of cold and cold pain. The TRPM8 protein is expressed in sensory neurons, and it is activated by cold temperatures and cooling agents, such as menthol and icilin whereas WS-12 and CPS-369 are the most selective agonist of TRPM8.

Synonyms: Long transient receptor potential channel 6 antibody|LTrpC-6 antibody|LTrpC6 antibody|MGC2849 antibody|Short form of the TRPM8 cationic channel antibody|Transient receptor potential cation channel subfamily M member 8 antibody|Transient receptor potential p8 antibody|transient receptor potential-p8 antibody|Trp p8 antibody|Trp-p8 antibody|Trpm8 antibody|TRPM8_HUMAN antibody|TRPP8 antibody

Gen-ID: 79054

UniProt: Q7Z2W7