SLC1A2 Antikörper (AA 461-574)

Produktnummer ABIN3043436

Produktdetails anti-SLC1A2 Antikörper

Target: SLC1A2 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2))

Bindungsspezifität: AA 461-574

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC1A2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 2(SLC1A2) detection. Tested with WB in Human,Mouse,Rat.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 2(SLC1A2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: solute carrier family 1 (glial high affinity glutamate transporter), member 2
Protein Name: Excitatory amino acid transporter 2

Aufreinigung: Immunogen affinity purified.

Immunogen: E.coli-derived human EAAT2 recombinant protein (Position: T461-K574). Human EAAT2 shares 96% amino acid (aa) sequence identity with both mouse and rat EAAT2.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for EAAT2 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-SLC1A2 Antikörper (ABIN3043436)

Ding, Zhang, Liu, Zhang, Ma, Bruce, Zhang: "Tumor necrosis factor-? promotes the expression of excitatory amino-acid transporter 2 in astrocytes: Optimal concentration and incubation time." in: Experimental and therapeutic medicine, Vol. 8, Issue 6, pp. 1909-1913, (2014) (PubMed).

Details zu SLC1A2

Target: SLC1A2 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2))

Andere Bezeichnung: SLC1A2 (SLC1A2 Produkte)

Synonyme: CG3159 antikoerper, Dmel\\CG3159 antikoerper, EAAT antikoerper, dEAAT2 antikoerper, dEaat2 antikoerper, Eaat antikoerper, GB16377 antikoerper, EAAT2 antikoerper, SLC1A2 antikoerper, Eaat2 antikoerper, Glt antikoerper, Glt-1 antikoerper, GLT-1 antikoerper, 1700091C19Rik antikoerper, 2900019G14Rik antikoerper, AI159670 antikoerper, GLT1 antikoerper, MGLT1 antikoerper, eaat2 antikoerper, fj34b12 antikoerper, slc1a2 antikoerper, wu:fj34b12 antikoerper, zgc:65897 antikoerper, Excitatory amino acid transporter 2 antikoerper, excitatory amino acid transporter 2 antikoerper, solute carrier family 1 member 2 antikoerper, solute carrier family 1 (glial high affinity glutamate transporter), member 2 antikoerper, solute carrier family 1 (glial high affinity glutamate transporter), member 2b antikoerper, Eaat2 antikoerper, Eaat-2 antikoerper, SLC1A2 antikoerper, VDBG_06180 antikoerper, EUBELI_01747 antikoerper, Trebr_0139 antikoerper, Slc1a2 antikoerper, slc1a2b antikoerper

Hintergrund: SLC1A2 is also known as EAAT2 or GLT-1. This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified.

Synonyms: EAA2_HUMAN antibody|EAAT2 antibody|Excitatory amino acid transporter 2 antibody|Excitotoxic amino acid transporter 2 antibody|Glial high affinity glutamate transporter antibody|GLT 1 antibody|GLT1 antibody|Glutamate aspartate transporter II antibody|Glutamate transporter 1 antibody|Glutamate/aspartate transporter II antibody|Slc1a2 antibody|Sodium dependent glutamate aspartate transporter 2 antibody|Sodium-dependent glutamate/aspartate transporter 2 antibody|solute carrier family 1 (glial high affinity glutamate transporter), member 2 antibody|Solute carrier family 1 glial high affinity glutamate transporter member 2 antibody|Solute carrier family 1 member 2 antibody

Gen-ID: 6506

UniProt: P43004

Pathways: Dicarboxylic Acid Transport