LUM Antikörper (AA 68-338)

Produktnummer ABIN3043386

Produktdetails anti-LUM Antikörper

Target: LUM (Lumican (LUM))

Bindungsspezifität: AA 68-338

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LUM Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Lumican(LUM) detection. Tested with WB, IHC-P, ELISA in Mouse.

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Lumican(LUM) detection. Tested with WB, IHC-P, ELISA in Mouse.
Gene Name: lumican
Protein Name: Lumican

Aufreinigung: Immunogen affinity purified.

Immunogen: E. coli-derived mouse Lumican recombinant protein (Position: I68-N338). Mouse Lumican shares 88.9% and 98.2% amino acid (aa) sequence identity with human and rat Lumican, respectively.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
ELISA: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse

Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu LUM

Target: LUM (Lumican (LUM))

Andere Bezeichnung: LUM (LUM Produkte)

Synonyme: MGC64527 antikoerper, zgc:86661 antikoerper, ldc antikoerper, slrr2d antikoerper, DKFZp468L1116 antikoerper, LDC antikoerper, SLRR2D antikoerper, Ldc antikoerper, lumican antikoerper, lumican L homeolog antikoerper, LUM antikoerper, lum.L antikoerper, lum antikoerper, CpipJ_CPIJ010209 antikoerper, Lum antikoerper

Hintergrund: Lumican, also known as LUM, is an extracellular matrix protein that, in humans, is encoded by the LUM gene on chromosome 12. Lumican is a major keratan sulfate proteoglycan of the cornea but is ubiquitously distributed in most mesenchymal tissues throughout the body. And Lumican is involved in collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. Corneal transparency is possible due to the exact alignment of collagen fibers by lumican (and keratocan) in the intrafibrillar space.

Synonyms: Keratan sulfate proteoglycan lumican antibody|KSPG lumican antibody|LDC antibody|LUM antibody|LUM_HUMAN antibody|Lumican antibody| Lumican precursor antibody|SLRR2D antibody

Gen-ID: 17022

UniProt: P51885

Pathways: Glycosaminoglycan Metabolic Process