SDHA Antikörper (N-Term)

Produktnummer ABIN3043074

Produktdetails anti-SDHA Antikörper

Target: SDHA (Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA))

Bindungsspezifität: AA 113-128, N-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SDHA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Succinate dehydrogenase[ubiquinone] flavoprotein subunit, mitochondrial(SDHA) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: NMEEDNWRWH FYDTVK

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Succinate dehydrogenase[ubiquinone] flavoprotein subunit, mitochondrial(SDHA) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: succinate dehydrogenase complex, subunit A, flavoprotein(Fp)
Protein Name: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human SDHA(113-128aa NMEEDNWRWHFYDTVK), identical to the related rat and mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu SDHA

Target: SDHA (Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA))

Andere Bezeichnung: SDHA (SDHA Produkte)

Synonyme: CG17246 antikoerper, Dmel\\CG17246 antikoerper, Scs-fp antikoerper, Sdh antikoerper, Sdha antikoerper, scs-fp antikoerper, sdh antikoerper, CMD1GG antikoerper, FP antikoerper, PGL5 antikoerper, SDH1 antikoerper, SDH2 antikoerper, SDHF antikoerper, 1500032O14Rik antikoerper, 2310034D06Rik antikoerper, 4921513A11 antikoerper, C81073 antikoerper, im:7141001 antikoerper, zgc:56051 antikoerper, Fp antikoerper, sdha-b antikoerper, Succinate dehydrogenase, subunit A (flavoprotein) antikoerper, succinate dehydrogenase complex flavoprotein subunit A antikoerper, succinate dehydrogenase complex, subunit A, flavoprotein (Fp) antikoerper, succinate dehydrogenase complex subunit A, flavoprotein (Fp) S homeolog antikoerper, SdhA antikoerper, SDHA antikoerper, Sdha antikoerper, sdha antikoerper, sdha.S antikoerper

Hintergrund: SDHA(Succinate dehydrogenase complex, subunit a, flavoprotein), also called SDH1, HOMOLOG OF, is a protein that in humans is encoded by the SDHA gene. The SDHA gene is mapped on 5p15.33. The SDHA gene is highly polymorphic. The gene that codes for the SDHA protein is nuclear, even though the protein is located in the inner membrane of the mitochondria. Heterozygous carriers of an SDHA mutation do not developparagangliomas as has been seen for mutations in the other subunits. In vitro functional expression studies in the yeast homolog showed that the mutation resulted in a loss of SDH activity and rendered the mutant SDHA protein more susceptible to proteolysis. The findings indicated that SDHA, like other SDH subunits, can act as a tumor suppressor gene.

Synonyms: CMD1GG antibody|DHSA_HUMAN antibody|Flavoprotein subunit of complex II antibody|Fp antibody|PGL5 antibody|SDH 2 antibody|SDH1 antibody|SDH2 antibody|SDHA antibody|SDHF antibody|Succinate dehydrogenase[ubiquinone] flavoprotein subunit antibody|Succinate dehydrogenase[ubiquinone] flavoprotein subunit mitochondrial antibody|Succinate dehydrogenase[ubiquinone] flavoprotein subunit, mitochondrial antibody|Succinate dehydrogenase complex flavoprotein subunit antibody|Succinate dehydrogenase complex flavoprotein subunit precursor antibody|Succinate dehydrogenase complex subunit A antibody|Succinate Dehydrogenase Complex subunit A Flavoprotein antibody

UniProt: P31040