ANGPTL3 Antikörper (N-Term)

Produktnummer ABIN3042916

Produktdetails anti-ANGPTL3 Antikörper

Target: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Bindungsspezifität: AA 32-48, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ANGPTL3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Angiopoietin-related protein 3(ANGPTL3) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: EPKSRFAMLD DVKILAN

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Angiopoietin-related protein 3(ANGPTL3) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: angiopoietin-like 3
Protein Name: Angiopoietin-related protein 3

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human ANGPTL3(32-48aa EPKSRFAMLDDVKILAN), identical to the related rat and mouse sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat, The detection limit for ANGPTL3 is approximately 1.5 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ANGPTL3

Target: ANGPTL3 (Angiopoietin-Like 3 (ANGPTL3))

Andere Bezeichnung: ANGPTL3 (ANGPTL3 Produkte)

Synonyme: fb60e11 antikoerper, fb66h02 antikoerper, wu:fb60e11 antikoerper, wu:fb66h02 antikoerper, zgc:111943 antikoerper, ANGPTL3 antikoerper, LOC100230785 antikoerper, ANG-5 antikoerper, ANGPT5 antikoerper, ANL3 antikoerper, FHBL2 antikoerper, hypl antikoerper, angiopoietin-like 3 antikoerper, angiopoietin like 3 antikoerper, angptl3 antikoerper, ANGPTL3 antikoerper, Angptl3 antikoerper

Hintergrund: ANGPTL3(Angiopoietin-Like 3), also known as ANGPT5, is a protein which in humans is encoded by the ANGPTL3 gene. The protein encoded by this gene is a member of the angiopoietin-like family of secreted factors. By radiation hybrid mapping and the use of surrounding genes, Conklin et al.(1999) mapped the ANGPTL3 gene to chromosome 1p31. It is predominantly expressed in the liver, and has the characteristic structure of angiopoietins, consisting of a signal peptide, N-terminal coiled-coil domain and the C-terminal fibrinogen(FBN)-like domain. Angptl3 also acts as dual inhibitor of lipoprotein lipase(LPL) and endothelial lipase(EL), and increases plasma triglyceride and HDL cholesterol in rodents. ANGPTL3 inhibit endothelial lipase to catalyze HDL-phospholipid and increase HDL-PL levels.

Synonyms: ANG 5 antibody|ANG-5 antibody|ANG5 antibody|Angiopoietin 5 antibody|Angiopoietin like 3 antibody|Angiopoietin related protein 3 antibody|Angiopoietin-5 antibody|Angiopoietin-like protein 3 antibody|Angiopoietin-related protein 3 antibody|ANGL3_HUMAN antibody|ANGPT5 antibody|ANGPTL3 antibody|ANL3 antibody|FHBL2 antibody|OTTHUMP00000010719 antibody|UNQ153/PRO179 antibody

UniProt: Q9Y5C1