Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

CXCR4 Antikörper (N-Term)

CXCR4 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042911
  • Target Alle CXCR4 Antikörper anzeigen
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Bindungsspezifität
    • 24
    • 15
    • 15
    • 12
    • 8
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 5
    • 5
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 31-43, N-Term
    Reaktivität
    • 157
    • 101
    • 76
    • 22
    • 13
    • 12
    • 11
    • 8
    • 6
    • 6
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 126
    • 29
    • 13
    • 11
    • 1
    Kaninchen
    Klonalität
    • 136
    • 44
    Polyklonal
    Konjugat
    • 100
    • 9
    • 8
    • 8
    • 7
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Dieser CXCR4 Antikörper ist unkonjugiert
    Applikation
    • 120
    • 58
    • 57
    • 36
    • 31
    • 25
    • 25
    • 25
    • 21
    • 12
    • 8
    • 6
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 4(CXCR4) detection. Tested with WB in Human.
    Sequenz
    EENANFNKIF LPT
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for C-X-C chemokine receptor type 4(CXCR4) detection. Tested with WB in Human.
    Gene Name: chemokine(C-X-C motif) receptor 4
    Protein Name: C-X-C chemokine receptor type 4
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human CXCR4(31-43aa EENANFNKIFLPT).
    Isotyp
    IgG
    Top Product
    Discover our top product CXCR4 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Konservierungsmittel
    Thimerosal (Merthiolate), Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Haltbarkeit
    12 months
  • Zhang, Wang, Yue, Liu, Liu: "Construction of a CXCL12-KDEL fusion gene to inhibit head and neck squamous cell carcinoma metastasis by intracellular sequestration of CXCR4." in: BioMed research international, Vol. 2015, pp. 195828, (2015) (PubMed).

    Zhu, Sun, Tan, Xu, Dai, Wang, Fan, Zhou: "Tacrolimus promotes hepatocellular carcinoma and enhances CXCR4/SDF‑1α expression in vivo." in: Molecular medicine reports, Vol. 10, Issue 2, pp. 585-92, (2015) (PubMed).

    Liu, Wang, Wang, Wang: "Anticancer effects of chemokine receptor 4(CXCR4) gene silenced by CXCR4-siRNA in nude mice model of ovarian cancer." in: Cell biochemistry and biophysics, Vol. 70, Issue 3, pp. 1893-900, (2014) (PubMed).

    Li, Chen, Yuan, Zhou, He, Zu, Qi: "CXCR4 expression in bladder transitional cell carcinoma and its relationship with clinicopathological features." in: Urologia internationalis, Vol. 92, Issue 2, pp. 157-63, (2014) (PubMed).

    Tan, Chang, Liu, Tang: "Silencing of CXCR4 inhibits tumor cell proliferation and neural invasion in human hilar cholangiocarcinoma." in: Gut and liver, Vol. 8, Issue 2, pp. 196-204, (2014) (PubMed).

    Wang, Guo, Han, Xu, Guo, Sun: "Distinct roles of different fragments of PDCD4 in regulating the metastatic behavior of B16 melanoma cells." in: International journal of oncology, Vol. 42, Issue 5, pp. 1725-33, (2013) (PubMed).

    Chen, Wang, Wang, Zhang, Liu, Pan, Wang, Chen, Jin, Wang: "Effect of short hairpin RNA-induced CXCR4 silence on ovarian cancer cell." in: Biomedicine & pharmacotherapy = Biome?decine & pharmacothe?rapie, Vol. 66, Issue 7, pp. 549-53, (2012) (PubMed).

    Lin, Zheng, Shen, Tang, Chen, Sun, Zhao, Yao: "Relationships between levels of CXCR4 and VEGF and blood-borne metastasis and survival in patients with osteosarcoma." in: Medical oncology (Northwood, London, England), Vol. 28, Issue 2, pp. 649-53, (2011) (PubMed).

    Wang, Cai, Han, Yang, Tong, Cao, Wu, Wang: "Silencing of CXCR4 blocks progression of ovarian cancer and depresses canonical Wnt signaling pathway." in: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, Vol. 21, Issue 6, pp. 981-7, (2011) (PubMed).

    Li, Deng, Gong, Bian, Dai, Wang: "Upregulation of CXCR4 favoring neural-like cells migration via AKT activation." in: Neuroscience research, Vol. 67, Issue 4, pp. 293-9, (2010) (PubMed).

    Zhang, Qi, Li, Zhang, Xu, Wang, Sun: "Chemokine CXCL12 and its receptor CXCR4 expression are associated with perineural invasion of prostate cancer." in: Journal of experimental & clinical cancer research : CR, Vol. 27, pp. 62, (2009) (PubMed).

  • Target
    CXCR4 (Chemokine (C-X-C Motif) Receptor 4 (CXCR4))
    Andere Bezeichnung
    CXCR4 (CXCR4 Produkte)
    Synonyme
    CD184 antikoerper, D2S201E antikoerper, FB22 antikoerper, HM89 antikoerper, HSY3RR antikoerper, LAP3 antikoerper, LCR1 antikoerper, LESTR antikoerper, NPY3R antikoerper, NPYR antikoerper, NPYRL antikoerper, NPYY3R antikoerper, WHIM antikoerper, Cmkar4 antikoerper, PB-CKR antikoerper, PBSF/SDF-1 antikoerper, Sdf1r antikoerper, CXC-R4-B antikoerper, CXCR-4-B antikoerper, cd184 antikoerper, cxcr4 antikoerper, fb22 antikoerper, hm89 antikoerper, hsy3rr antikoerper, lap3 antikoerper, lcr1 antikoerper, lestr antikoerper, npy3r antikoerper, npyr antikoerper, npyrl antikoerper, npyy3r antikoerper, xcxcr4 antikoerper, CXC-R4 antikoerper, CXCR-4 antikoerper, d2s201e antikoerper, whim antikoerper, CXC-R4-A antikoerper, CXCR-4-A antikoerper, xCXCR4 antikoerper, CXCR4 antikoerper, cb403 antikoerper, zgc:109863 antikoerper, cb824 antikoerper, C-X-C motif chemokine receptor 4 antikoerper, chemokine (C-X-C motif) receptor 4 antikoerper, C-X-C motif chemokine receptor 4 S homeolog antikoerper, C-X-C chemokine receptor type 4 antikoerper, C-X-C motif chemokine receptor 4 L homeolog antikoerper, chemokine (C-X-C motif), receptor 4b antikoerper, chemokine (C-X-C motif) receptor 4a antikoerper, CXCR4 antikoerper, Cxcr4 antikoerper, cxcr4.S antikoerper, cxcr4 antikoerper, LOC100049444 antikoerper, cxcr4.L antikoerper, cxcr4b antikoerper, cxcr4a antikoerper
    Hintergrund
    CXCR4 (Chemokine,CXC Motif, Receptor 4), also known as FUSIN or NPY3R, is a protein that in humans is encoded by the CXCR4 gene. It is the receptor for the CXC chemokine SDF1 that has essential functions on embryo organogenesis, immunological functions and T lymphocyte trafficking. CXCR4 is the only SDF1 receptor identified so far. This suggests that CXCR4 expression is critical for the biological effects of SDF1. CXCR4 is also a seven-transmembrane-spanning, G-protein-coupled receptor for the CXC chemokine PBSF/SDF-1. It functions as a co-receptor for T-cell-line tropic human immunodeficiency virus HIV-1. It was concluded that PBSF/SDF-1 and CXCR4 define a new signalling system for organ vascularization.

    Synonyms: C-X-C chemokine receptor type 4 antibody|CD184 antibody|CD184 antigen antibody|Chemokine(C X C motif) receptor 4 antibody|Chemokine CXC Motif Receptor 4 antibody|CXC-R4 antibody|CXCR-4 antibody|CXCR4 antibody|CXCR4_HUMAN antibody|D2S201E antibody|FB22 antibody|Fusin antibody|HM89 antibody|HSY3RR antibody|LAP 3 antibody|LAP3 antibody|LCR1 antibody|LESTR antibody|Leukocyte derived seven transmembrane domain receptor antibody|Leukocyte-derived seven transmembrane domain receptor antibody|Lipopolysaccharide associated protein 3 antibody|Neuropeptide Y receptor Y3 antibody|NPY3R antibody|NPYR antibody|NPYRL antibody|NPYY3 antibody|NPYY3R antibody|Probable G protein coupled receptor lcr1 homolog antibody|SDF 1 receptor antibody|SDF-1 receptor antibody|SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR antibody|Stromal cell derived factor 1 receptor antibody|Stromal cell-derived factor 1 receptor antibody|WHIM antibody
    UniProt
    P61073
    Pathways
    Regulation of Cell Size, CXCR4-mediated Signaling Events
Sie sind hier:
Kundenservice