GJC1 Antikörper (C-Term)

Produktnummer ABIN3042835

Produktdetails anti-GJC1 Antikörper

Target: GJC1 (Gap Junction Protein, gamma 1, 45kDa (GJC1))

Bindungsspezifität: AA 308-322, C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GJC1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Gap junction gamma-1 protein(GJC1) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: KIAYKQNKAN TAQEQ

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse, rat
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Gap junction gamma-1 protein(GJC1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: gap junction protein, gamma 1, 45 kDa
Protein Name: Gap junction gamma-1 protein

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Connexin 45(308-322aa KIAYKQNKANTAQEQ), different from the related mouse and rat sequences by one amino acid.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Predicted Species: Mouse, Rat
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Referenzen für anti-GJC1 Antikörper (ABIN3042835)

Zeng, Li, Li, Li, Xiao, Chu, Yang: "Effect of Novel Gasotransmitter hydrogen sulfide on renal fibrosis and connexins expression in diabetic rats." in: Bioengineered, Vol. 7, Issue 5, pp. 314-320, (2017) (PubMed).

Details zu GJC1

Target: GJC1 (Gap Junction Protein, gamma 1, 45kDa (GJC1))

Andere Bezeichnung: GJC1 (GJC1 Produkte)

Synonyme: CX45 antikoerper, GJA7 antikoerper, cx45 antikoerper, gja7 antikoerper, MGC52735 antikoerper, GJD3 antikoerper, GJC1 antikoerper, C130009G16Rik antikoerper, Cnx45 antikoerper, Cx45 antikoerper, Gja-7 antikoerper, Gja7 antikoerper, gap junction protein gamma 1 antikoerper, gap junction protein gamma 1 L homeolog antikoerper, gap junction protein, delta 3, 31.9kDa antikoerper, gap junction protein, gamma 1 antikoerper, Gap junction gamma-1 protein antikoerper, GJC1 antikoerper, gjc1.L antikoerper, GJD3 antikoerper, Gjc1 antikoerper, gjc1 antikoerper

Hintergrund: Gap junction gamma-1 protein(GJC1), also known as gap junction alpha-7 protein(GJA7) or connexin 45(Cx45), is a protein that in humans is encoded by the GJC1 gene. The International Radiation Hybrid Mapping Consortium mapped the GJA7 gene to chromosome 17q21.31. This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell.

Synonyms: Connexin 45 antibody|Connexin-45 antibody|Connexin45 antibody|CX 31.9 antibody|CX 45 antibody|CX31.9 antibody|Cx45 antibody|CXG1_HUMAN antibody|DKFZp686P0738 antibody|Gap junction alpha 7 protein antibody|Gap junction alpha-7 protein antibody|Gap junction gamma 1 protein antibody|Gap junction gamma-1 protein antibody|Gap junction protein alpha 7 45 kDa antibody|Gap junction protein alpha 7 antibody|Gap junction protein, gamma 1, 45 kDa antibody|GJA 7 antibody|GJA7 antibody|GJC1 antibody|GJD3 antibody

UniProt: P36383

Pathways: Cell-Cell Junction Organization