IKBKG Antikörper (N-Term)

Produktnummer ABIN3042676

Produktdetails anti-IKBKG Antikörper

Target: IKBKG (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))

Bindungsspezifität: AA 1-15, N-Term

Reaktivität: Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IKBKG Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for NF-kappa-B essential modulator(IKBKG) detection. Tested with WB in Mouse.

Sequenz: MNKHPWKNQL SEMVQ

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for NF-kappa-B essential modulator(IKBKG) detection. Tested with WB in Mouse.
Gene Name: inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma
Protein Name: NF-kappa-B essential modulator(NEMO)

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of mouse IKK gamma(1-15aa MNKHPWKNQLSEMVQ), different from the relative rat sequence by three amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu IKBKG

Target: IKBKG (Inhibitor of kappa Light Polypeptide Gene Enhancer in B-Cells, Kinase gamma (IKBKG))

Andere Bezeichnung: IKBKG (IKBKG Produkte)

Synonyme: AMCBX1 antikoerper, FIP-3 antikoerper, FIP3 antikoerper, Fip3p antikoerper, IKK-gamma antikoerper, IP antikoerper, IP1 antikoerper, IP2 antikoerper, IPD2 antikoerper, NEMO antikoerper, ZC2HC9 antikoerper, 1110037D23Rik antikoerper, AI848108 antikoerper, AI851264 antikoerper, AW124339 antikoerper, IKK[g] antikoerper, Nemo antikoerper, nemo antikoerper, fj33c07 antikoerper, wu:fj33c07 antikoerper, zgc:113492 antikoerper, MGC97885 antikoerper, IKBKG antikoerper, IKBKG_1 antikoerper, IKBKG_2 antikoerper, CG16910 antikoerper, DmIKK-gamma antikoerper, DmIKKgamma antikoerper, Dmel\\CG16910 antikoerper, Dmikkgamma antikoerper, IKK antikoerper, IKK[[gamma]] antikoerper, IKKg antikoerper, IKKgamma antikoerper, KEY antikoerper, Kenny antikoerper, Key antikoerper, dIKK antikoerper, dIKK-gamma antikoerper, dmIKKgamma antikoerper, inhibitor of nuclear factor kappa B kinase subunit gamma antikoerper, inhibitor of kappaB kinase gamma antikoerper, inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase gamma antikoerper, inhibitor of nuclear factor kappa B kinase subunit gamma L homeolog antikoerper, kenny antikoerper, IKBKG antikoerper, Ikbkg antikoerper, ikbkg antikoerper, ikbkg.L antikoerper, IKBKG_1 antikoerper, key antikoerper

Hintergrund: NF-kappa-B essential modulator (NEMO), also known as inhibitor of nuclear factor kappa-B kinase subunit gamma (IKK-γ), is a protein that in humans is encoded by the IKBKG gene. This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in incontinentia pigmenti, hypohidrotic ectodermal dysplasia, and several other types of immunodeficiencies. A pseudogene highly similar to this locus is located in an adjacent region of the X chromosome.

Synonyms: IkB kinase associated protein 1 antibody|IkB kinase subunit gamma antibody|Inhibitor of nuclear factor kappa B kinase subunit gamma antibody|AMCBX1 antibody|FIP 3 antibody|FIP-3 antibody|FIP3 antibody|Fip3p antibody|I kappa B kinase gamma antibody|I-kappa-B kinase subunit gamma antibody|IkB kinase associated protein 1 antibody|IkB kinase gamma subunit antibody|IkB kinase subunit gamma antibody|IkB kinase-associated protein 1 antibody|IKBKG antibody|IKK-gamma antibody|IKKAP 1 antibody|IKKAP1 antibody|IKKG antibody|Incontinentia pigmenti antibody|Inhibitor of kappa light polypeptide gene enhancer in B cells kinase gamma antibody|Inhibitor of kappa light polypeptide gene enhancer in B cells, kinase gamma antibody|Inhibitor of nuclear factor kappa B kinase gamma subunit antibody|Inhibitor of nuclear factor kappa B kinase subunit gamma antibody|Inhibitor of nuclear factor kappa-B kinase subunit gamma antibody|IP 1 antibody|IP 2 antibody|IP antibody|IP1 antibody|IP2 antibody|IPD2 antibody|NEMO antibody|NEMO_HUMAN antibody|NF kappa B essential modifier antibody|NF kappa B essential modulator antibody|NF kappaB essential modifier antibody|NF kappaB essential modulator antibody|NF-kappa-B essential modifier antibody|NF-kappa-B essential modulator antibody|NFkappaB essential modulator antibody|ZC2HC9 antibody

UniProt: O88522

Pathways: NF-kappaB Signalweg, RTK Signalweg, T-Zell Rezeptor Signalweg, TLR Signalweg, Fc-epsilon Rezeptor Signalübertragung, Activation of Innate immune Response, M Phase, Production of Molecular Mediator of Immune Response, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, BCR Signaling, Ubiquitin Proteasome Pathway, S100 Proteine