TNFRSF11A Antikörper (N-Term)

Produktnummer ABIN3042604

Produktdetails anti-TNFRSF11A Antikörper

Target: TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Bindungsspezifität: AA 29-44, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNFRSF11A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 11A(TNFRSF11A) detection. Tested with WB, IHC-P in Human.

Sequenz: QIAPPCTSEK HYEHLG

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Tumor necrosis factor receptor superfamily member 11A(TNFRSF11A) detection. Tested with WB, IHC-P in Human.
Gene Name: tumor necrosis factor receptor superfamily, member 11a, NFKB activator
Protein Name: Tumor necrosis factor receptor superfamily member 11A

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human RANK(29-44aa QIAPPCTSEKHYEHLG).

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu TNFRSF11A

Target: TNFRSF11A (Tumor Necrosis Factor Receptor Superfamily, Member 11a, NFKB Activator (TNFRSF11A))

Andere Bezeichnung: TNFRSF11A (TNFRSF11A Produkte)

Synonyme: RANK antikoerper, RGD1563614 antikoerper, TNFRSF11A antikoerper, Ly109 antikoerper, ODFR antikoerper, OFE antikoerper, Rank antikoerper, TRANCE-R antikoerper, mRANK antikoerper, CD265 antikoerper, FEO antikoerper, LOH18CR1 antikoerper, OPTB7 antikoerper, OSTS antikoerper, PDB2 antikoerper, TRANCER antikoerper, TNF receptor superfamily member 11A antikoerper, TNF receptor superfamily member 11a antikoerper, tumor necrosis factor receptor superfamily, member 11a, NFKB activator antikoerper, Tnfrsf11a antikoerper, TNFRSF11A antikoerper

Hintergrund: Receptor Activator of Nuclear Factor K B(RANK), also known as TRANCE Receptor, is a type I membrane protein that is expressed on the surface of osteoclasts and is involved in their activation upon ligand binding. RANK is also expressed on dendritic cells and facilitates immune signaling. RANKL(Receptor Activator for Nuclear Factor K B Ligand) is found on the surface of stromal cells, osteoblasts, and T cells. By analysis of somatic cell and radiation hybrid panels, Anderson et al.(1997) mapped the RANK gene to 18q22.1.

Synonyms: Activator of NFKB antibody|CD 265 antibody|CD265 antibody|CD265 antigen antibody|EOF antibody|FEO antibody|LOH18CR1 antibody|Loss of heterozygosity 18 chromosomal region 1 antibody|mRANK antibody|NFKB activator antibody|ODFR antibody|OFE antibody|OPTB7 antibody|Osteoclast differentiation factor receptor antibody|OSTS antibody|PDB 2 antibody|PDB2 antibody|RANK antibody|Receptor activator of NF KB antibody|Receptor activator of NF-KB antibody|receptor activator of nuclear factor kappa B antibody|TNFRSF 11A antibody|TNFRSF11A antibody|TNFSF11 antibody|TNR11_HUMAN antibody|TRANCE R antibody|TRANCER antibody|Tumor necrosis factor receptor superfamily member 11a NFKB activator antibody|Tumor necrosis factor receptor superfamily member 11a activator of NFKB antibody|Tumor Necrosis Factor Receptor Superfamily Member 11a antibody

UniProt: Q9Y6Q6

Pathways: NF-kappaB Signalweg