ATG7 Antikörper (C-Term)

Produktnummer ABIN3042570

Produktdetails anti-ATG7 Antikörper

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Bindungsspezifität: AA 652-669, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ATG7 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Ubiquitin-like modifier-activating enzyme ATG7(ATG7) detection. Tested with WB in Human,Mouse,Rat.

Sequenz: KVLDQYEREG FNFLAKVF

Kreuzreaktivität (Details): Predicted Cross Reactivity: mouse
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Produktmerkmale: Rabbit IgG polyclonal antibody for Ubiquitin-like modifier-activating enzyme ATG7(ATG7) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: autophagy related 7
Protein Name: Ubiquitin-like modifier-activating enzyme ATG7

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human Apg7(652-669aa KVLDQYEREGFNFLAKVF), different from the related mouse sequence by one amino acid, and from the related rat sequence by two amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat, Predicted Species: Mouse
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Konservierungsmittel: Thimerosal (Merthiolate), Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-ATG7 Antikörper (ABIN3042570)

Shen, Li, Cai, Liu, Wang, Gan, Li, Wang, Sun, Deng, Liu, Li: "Erbin exerts a protective effect against inflammatory bowel disease by suppressing autophagic cell death." in: Oncotarget, Vol. 9, Issue 15, pp. 12035-12049, (2018) (PubMed).

He, Wang, Han, Jin, Li, Wu, Ma, Cheng, Tang, Yang, Liu: "Nrf2 signalling and autophagy are involved in diabetes mellitus-induced defects in the development of mouse placenta." in: Open biology, Vol. 6, Issue 7, (2017) (PubMed).

Details zu ATG7

Target: ATG7 (ATG7 Autophagy Related 7 (ATG7))

Andere Bezeichnung: ATG7 (ATG7 Produkte)

Synonyme: APG7-LIKE antikoerper, APG7L antikoerper, GSA7 antikoerper, D8 antikoerper, UBA1B antikoerper, UBE1L antikoerper, UBE2 antikoerper, Ube1l antikoerper, 1300004C08Rik antikoerper, AO090001000744 antikoerper, atg7 antikoerper, 1810013K23Rik antikoerper, Agp7 antikoerper, Apg7l antikoerper, Atg7l antikoerper, ATAPG7 antikoerper, ATATG7 antikoerper, ATG7 antikoerper, AUTOPHAGY 7 antikoerper, AUTOPHAGY-RELATED 7 antikoerper, K15I22.10 antikoerper, K15I22_10 antikoerper, autophagy related 7 antikoerper, ubiquitin like modifier activating enzyme 7 antikoerper, ubiquitin-like modifier activating enzyme 7 antikoerper, autophagy-related protein 7 antikoerper, Autophagy-related protein 7 antikoerper, Apg7p antikoerper, ThiF family protein antikoerper, ubiquitin-like conjugating enzyme Atg7 antikoerper, ATG7 antikoerper, UBA7 antikoerper, Uba7 antikoerper, ANI_1_3368024 antikoerper, AOR_1_1338164 antikoerper, PTRG_02236 antikoerper, PAAG_00287 antikoerper, PITG_12537 antikoerper, atg7 antikoerper, Atg7 antikoerper, APG7 antikoerper

Hintergrund: Autophagy-related protein 7 is a protein that in humans is encoded by the ATG7 gene. It is mapped to 3p25.3. This gene was identified based on homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae APG7. In the yeast, the protein appears to be required for fusion of peroxisomal and vacuolar membranes. The protein also shows homology to the ATP-binding and catalytic sites of the E1 ubiquitin activating enzymes. ATG7 is essential for the Apg12 conjugation system that mediates membrane fusion in autophagy. It is found that when nutrients are limited, ATG7 can regulate p53-dependent cell cycle and cell death pathways.

Synonyms: 1810013K23Rik antibody|Apg 7 antibody|APG7 autophagy 7 like antibody|APG7 autophagy 7-like(S. cerevisiae) antibody|APG7 like antibody|APG7, S. cerevisiae, homolog of antibody|APG7-like antibody|APG7L antibody|ATG 7 antibody|ATG12-activating enzyme E1 ATG7 antibody|atg7 antibody|ATG7 autophagy related 7 homolog(S. cerevisiae) antibody|ATG7 autophagy related 7 homolog antibody|Atg7l antibody|Autophagy 7, S. cerevisiae, homolog of antibody|Autophagy related protein 7 antibody|Autophagy-related 7(yeast) antibody|Autophagy-related protein 7 antibody|DKFZp434N0735 antibody|GSA 7 antibody|GSA7 antibody|hAGP7 antibody|Ubiquitin activating enzyme E1 like protein antibody|Ubiquitin-activating enzyme E1-like protein antibody|Ubiquitin-like modifier-activating enzyme ATG7 antibody

UniProt: O95352

Pathways: Response to Water Deprivation, Autophagie