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PIN1 Antikörper (AA 1-163)

PIN1 Reaktivität: Human, Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042501
  • Target Alle PIN1 Antikörper anzeigen
    PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
    Bindungsspezifität
    • 15
    • 13
    • 10
    • 9
    • 9
    • 8
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-163
    Reaktivität
    • 109
    • 51
    • 36
    • 8
    • 8
    • 6
    • 5
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 101
    • 13
    • 2
    • 1
    Kaninchen
    Klonalität
    • 103
    • 14
    Polyklonal
    Konjugat
    • 58
    • 13
    • 12
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PIN1 Antikörper ist unkonjugiert
    Applikation
    • 86
    • 49
    • 39
    • 31
    • 20
    • 19
    • 14
    • 14
    • 13
    • 13
    • 5
    • 5
    • 3
    • 2
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1(PIN1) detection. Tested with WB in Human,Mouse,Rat.
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1(PIN1) detection. Tested with WB in Human,Mouse,Rat.
    Gene Name: peptidylprolyl cis/trans isomerase, NIMA-interacting 1
    Protein Name: Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    E.coli-derived human Pin1 recombinant protein (Position: M1-E163). Human Pin1 shares 95% amino acid (aa) sequence identity with mouse Pin1.
    Isotyp
    IgG
    Top Product
    Discover our top product PIN1 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Pin1 is approximately 0.1 ng/lane under reducing conditions.
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    PIN1 (Peptidylprolyl Cis/trans Isomerase, NIMA-Interacting 1 (PIN1))
    Andere Bezeichnung
    PIN1 (PIN1 Produkte)
    Synonyme
    DOD antikoerper, UBL5 antikoerper, dod antikoerper, ubl5 antikoerper, pin1 antikoerper, pin1a antikoerper, 0610025L01Rik antikoerper, D9Bwg1161e antikoerper, pin1b antikoerper, zgc:73206 antikoerper, PPIase pin1 antikoerper, MdPin1 antikoerper, Pin1 antikoerper, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 antikoerper, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 S homeolog antikoerper, protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting 1 antikoerper, peptidylprolyl cis/trans isomerase, NIMA-interacting 1 L homeolog antikoerper, peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 antikoerper, peptidyl-prolyl cis-trans isomerase Pin1 antikoerper, PIN1 antikoerper, Pin1 antikoerper, pin1 antikoerper, pin1.S antikoerper, pin1.L antikoerper, ppiD antikoerper, PITG_11123 antikoerper, LOC103419188 antikoerper
    Hintergrund
    Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1, also called DOD, is an enzyme that in humans is encoded by the PIN1 gene. It is mapped to 19p13.2. The enzyme binds to a subset of proteins and thus plays a role as a post phospho PIN1rol in regulating protein function. Studies have shown that the deregulation of PIN1 may play a pivotal role in various diseases. Notably, the up-regulation of PIN1 may be implicated in certain cancers, and the down-regulation of Pin1 may be implicated in Alzheimer's disease. Inhibitors of PIN1 may have therapeutic implications for cancer and immune disorders. PIN1 activity regulates the outcome of proline-directed kinase (e.g. MAPK, CDK or GSK3) signalling and consequently regulates cell proliferation (in part through control of cyclin D1 levels and stability) and cell survival. PIN1 also has an essential role in maintaining cell proliferation and regulating cyclin D1 function.

    Synonyms: DOD antibody|DODO, Drosophila, homolog of antibody|FLJ40239 antibody|FLJ77628 antibody|MGC10717 antibody|NIMA interacting 1 antibody|Peptidyl prolyl cis trans isomerase NIMA interacting 1 antibody|Peptidyl prolyl cis/trans isomerase NIMA interacting antibody|Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 antibody|Peptidyl-prolyl cis-trans isomerase pin1 antibody|Peptidylprolyl cis/trans isomerase NIMA interacting 1 antibody|Pin 1 antibody|Pin1 antibody|PIN1_HUMAN antibody|PPIase Pin1 antibody|Prolyl isomerase antibody|Protein (peptidylprolyl cis/trans isomerase) NIMA interacting 1 antibody|Protein NIMA interacting 1 antibody|Rotamase Pin1 antibody|UBL 5 antibody|UBL5 antibody
    Gen-ID
    5300
    UniProt
    Q13526
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