RAP1A Antikörper (C-Term)

Produktnummer ABIN3042496

Produktdetails anti-RAP1A Antikörper

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Bindungsspezifität: AA 156-181, C-Term

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RAP1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Ras-related protein Rap-1A(RAP1A) detection. Tested with WB in Human,Rat.

Sequenz: EIFYDLVRQI NRKTPVEKKK PKKKSC

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Ras-related protein Rap-1A(RAP1A) detection. Tested with WB in Human,Rat.
Gene Name: RAP1A, member of RAS oncogene family
Protein Name: Ras-related protein Rap-1A

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human RAP1A (156-181aa EIFYDLVRQINRKTPVEKKKPKKKSC), identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu RAP1A

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Andere Bezeichnung: RAP1A (RAP1A Produkte)

Synonyme: KREV-1 antikoerper, KREV1 antikoerper, RAP1 antikoerper, SMGP21 antikoerper, AI848598 antikoerper, G-22K antikoerper, Krev-1 antikoerper, Rap1 antikoerper, RAP-1A antikoerper, rap 1A antikoerper, wu:fc66g06 antikoerper, zgc:86676 antikoerper, krev-1 antikoerper, krev1 antikoerper, rap1 antikoerper, RAP1A, member of RAS oncogene family antikoerper, RAS-related protein 1a antikoerper, RAP1A, member of RAS oncogene family a antikoerper, RAP1A, member of RAS oncogene family L homeolog antikoerper, RAP1A antikoerper, Rap1a antikoerper, rap1aa antikoerper, rap1a.L antikoerper

Hintergrund: Ras-related protein Rap-1A is a protein that in humans is encoded by the RAP1A gene. This gene encodes a member of the Ras family of small GTPases. The encoded protein undergoes a change in conformational state and activity, depending on whether it is bound to GTP or GDP. And it is activated by several types of guanine nucleotide exchange factors (GEFs), and inactivated by two groups of GTPase-activating proteins (GAPs). The activation status of the encoded protein is therefore affected by the balance of intracellular levels of GEFs and GAPs. Additionally, the encoded protein regulates signaling pathways that affect cell proliferation and adhesion, and may play a role in tumor malignancy. Pseudogenes of this gene have been defined on chromosomes 14 and 17. Alternative splicing results in multiple transcript variants.

Synonyms: C21KG antibody|G 22K antibody|G-22K antibody|GTP binding protein smg p21A antibody|GTP-binding protein smg p21A antibody|KREV 1 antibody|KREV1 antibody|OTTHUMP00000013741 antibody|RAP 1A antibody|RAP1 antibody|RAP1A antibody|RAP1A member of RAS oncogene family antibody|RAP1A_HUMAN antibody|Ras related protein Krev 1 antibody|Ras related protein Rap 1A antibody|RAS related protein RAP1A antibody|Ras-related protein Krev-1 antibody|Ras-related protein Rap-1A antibody|SMGP21 antibody

Gen-ID: 5906

UniProt: P62834

Pathways: T-Zell Rezeptor Signalweg, Neurotrophin Signalübertragung, Signaling of Hepatocyte Growth Factor Receptor