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HAVCR1 Antikörper (C-Term)

HAVCR1 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042438
  • Target Alle HAVCR1 Antikörper anzeigen
    HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
    Bindungsspezifität
    • 12
    • 9
    • 8
    • 6
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 321-359, C-Term
    Reaktivität
    • 99
    • 48
    • 34
    • 6
    • 6
    • 5
    Human
    Wirt
    • 102
    • 24
    • 5
    • 2
    Kaninchen
    Klonalität
    • 105
    • 28
    • 1
    Polyklonal
    Konjugat
    • 65
    • 15
    • 14
    • 6
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser HAVCR1 Antikörper ist unkonjugiert
    Applikation
    • 93
    • 41
    • 32
    • 17
    • 16
    • 12
    • 11
    • 11
    • 11
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Hepatitis A virus cellular receptor 1(HAVcr-1)(HAVCR1) detection. Tested with WB in Human.
    Sequenz
    QQLSVSFSSL QIKALQNAVE KEVQAEDNIY IENSLYATD
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Hepatitis A virus cellular receptor 1(HAVcr-1)(HAVCR1) detection. Tested with WB in Human.
    Gene Name: hepatitis A virus cellular receptor 1
    Protein Name: Hepatitis A virus cellular receptor 1(HAVcr-1)
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the C-terminus of human TIM 1 (321-359aa QQLSVSFSSLQIKALQNAVEKEVQAEDNIYIENSLYATD).
    Isotyp
    IgG
    Top Product
    Discover our top product HAVCR1 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Target
    HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))
    Andere Bezeichnung
    HAVCR1 (HAVCR1 Produkte)
    Synonyme
    HAVCR antikoerper, HAVCR-1 antikoerper, KIM-1 antikoerper, KIM1 antikoerper, TIM antikoerper, TIM-1 antikoerper, TIM1 antikoerper, TIMD-1 antikoerper, TIMD1 antikoerper, Kim1 antikoerper, HAVCR1 antikoerper, LOC100226241 antikoerper, AI503787 antikoerper, Tim1 antikoerper, Timd1 antikoerper, hepatitis A virus cellular receptor 1 antikoerper, hepatitis A virus cellular receptor 1 homolog antikoerper, HAVCR1 antikoerper, Havcr1 antikoerper, LOC100226241 antikoerper
    Substanzklasse
    Virus
    Hintergrund
    KIM1 (KIDNEY INJURY MOLECULE 1), also known as HAVCR1, HAVCR or TIM1, is a protein that in humans is encoded by the KIM1 gene. The KIM1 gene is mapped to 5q33.3. Biochemical, mutational, and cell adhesion analyses confirm that Tim1 is capable of homophilic Tim-Tim interactions. The features identified in murine KIM1 are conserved in human KIM1. The KIM1 protein is indeed a receptor for the virus through the infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV. Using a monoclonal antibody to mouse Tim1, Tim1 is expressed after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions. Ectopic expression of KIM1 during mouse T-cell differentiation leads to production of the Th2-type cytokine Il4, but not the Th1-type cytokine Ifng. KIM1-expressing epithelial cells internalized apoptotic bodies, and Kim1 is directly responsible for phagocytosis in cultured primary rat tubule epithelial cells and in porcine and canine epithelial cell lines.

    Synonyms: HAVCR 1 antibody|HAVcr-1 antibody|HAVCR1 antibody|Hepatitis A virus cellular receptor 1 antibody|Kidney injury molecule 1 antibody|KIM 1 antibody|KIM-1 antibody|T cell immunoglobin domain and mucin domain protein 1 antibody|T-cell immunoglobulin and mucin domain-containing protein 1 antibody|T-cell membrane protein 1 antibody|TIM antibody|TIM-1 antibody|TIM1 antibody|TIMD 1 antibody|TIMD-1 antibody|TIMD1 antibody|TIMD1_HUMAN antibody
    Gen-ID
    26762
    UniProt
    Q96D42
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