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Fascin Antikörper (N-Term)

FSCN1 Reaktivität: Human, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3042407
  • Target Alle Fascin (FSCN1) Antikörper anzeigen
    Fascin (FSCN1)
    Bindungsspezifität
    • 16
    • 15
    • 5
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 42-73, N-Term
    Reaktivität
    • 90
    • 52
    • 30
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Ratte
    Wirt
    • 76
    • 36
    • 1
    • 1
    Kaninchen
    Klonalität
    • 67
    • 47
    Polyklonal
    Konjugat
    • 47
    • 13
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    Dieser Fascin Antikörper ist unkonjugiert
    Applikation
    • 80
    • 47
    • 38
    • 32
    • 28
    • 28
    • 20
    • 14
    • 11
    • 7
    • 6
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB)
    Verwendungszweck
    Rabbit IgG polyclonal antibody for Fascin(FSCN1) detection. Tested with WB in Human,Rat.
    Sequenz
    KKQIWTLEQP PDEAGSAAVC LRSHLGRYLA AD
    Kreuzreaktivität (Details)
    No cross reactivity with other proteins.
    Produktmerkmale
    Rabbit IgG polyclonal antibody for Fascin(FSCN1) detection. Tested with WB in Human,Rat.
    Gene Name: fascin homolog 1, actin-bundling protein (Strongylocentrotus purpuratus)
    Protein Name: Fascin
    Aufreinigung
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human Fascin (42-73aa KKQIWTLEQPPDEAGSAAVCLRSHLGRYLAAD), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.
    Isotyp
    IgG
    Top Product
    Discover our top product FSCN1 Primärantikörper
  • Applikationshinweise
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Rat
    Notes: Tested Species: Species with positive results.
    Other applications have not been tested. Optimal dilutions should be determined by end users.
    Kommentare

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Lyophilized
    Rekonstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Konzentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handhabung
    Avoid repeated freezing and thawing.
    Lagerung
    4 °C/-20 °C
    Informationen zur Lagerung
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Jiang, Wang, Chen: "Overexpression of FOXM1 is associated with metastases of nasopharyngeal carcinoma." in: Upsala journal of medical sciences, Vol. 119, Issue 4, pp. 324-32, (2014) (PubMed).

  • Target
    Fascin (FSCN1)
    Andere Bezeichnung
    FSCN1 (FSCN1 Produkte)
    Synonyme
    CG15331 antikoerper, CG1536 antikoerper, CG32858 antikoerper, Dmel\\CG32858 antikoerper, SN antikoerper, Sn antikoerper, fs(1)A1057 antikoerper, fs(1)K1421 antikoerper, fs(1)K418 antikoerper, fs(1)K473 antikoerper, fs(1)K743 antikoerper, fs(1)M45 antikoerper, p55 antikoerper, snl antikoerper, MGC75811 antikoerper, fscn1 antikoerper, sb:cb589 antikoerper, zgc:153632 antikoerper, AI663989 antikoerper, Fan1 antikoerper, fascin-1 antikoerper, Fascin antikoerper, fscn antikoerper, FAN1 antikoerper, HSN antikoerper, SNL antikoerper, fascin antikoerper, singed antikoerper, fascin actin-bundling protein 1 antikoerper, fascin actin-bundling protein 1a antikoerper, fascin actin-bundling protein 1 L homeolog antikoerper, sn antikoerper, fscn1 antikoerper, fscn1a antikoerper, Fscn1 antikoerper, fscn1.L antikoerper, FSCN1 antikoerper
    Hintergrund
    Fascin is an actin cross-linking protein. The Fascin gene contains 5 exons and spans 7 kb. It is a 54-58 kilodalton monomeric actin filament bundling protein originally isolated from sea urchin egg but also found in Drosophila and vertebrates, including humans. Fascin (from the Latin for bundle) is spaced at 11 nanometre intervals along the filament. The bundles in cross section are seen to be hexagonally packed, and the longitudinal spacing is compatible with a model where fascin cross-links at alternating 4 and 5 actins. It is calcium insensitive and monomeric. Fascin binds beta-catenin, and colocalizes with it at the leading edges and borders of epithelial and endothelial cells. The role of Fascin in regulating cytoskeletal structures for the maintenance of cell adhesion, coordinating motility and invasion through interactions with signalling pathways is an active area of research especially from the cancer biology perspective. Abnormal fascin expression or function has been implicated in breast cancer, colon cancer, esophageal squamous cell carcinoma, gallbladder cancer and prostate cancer.

    Synonyms: 55 kDa actin bundling protein antibody|55 kDa actin-bundling protein antibody|Actin bundling protein antibody|actin bundling protein, 55-KD antibody|FAN 1 antibody|FAN1 antibody|Fascin 1 antibody|Fascin antibody|Fascin homolog 1 actin bundling protein (Strongylocentrotus purpuratus) antibody|Fascin homolog 1 antibody|Fascin, sea urchin, homolog of, 1 antibody|Fascin1 antibody| FLJ38511 antibody|FSCN 1 antibody|FSCN1 antibody|FSCN1_HUMAN antibody|HSN antibody|p55 antibody|Singed (Drosophila) like (sea urchin fascin homolog like) antibody|Singed drosophila homolog like antibody|Singed like (fascin homolog sea urchin) (Drosophila) antibody| Singed like (fascin homolog sea urchin) antibody|Singed like protein antibody|Singed, drosophila, homolog of antibody|Singed-like protein antibody|SNL antibody|Strongylocentrotus purpuratus antibody
    Gen-ID
    6624
    UniProt
    Q16658
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