WNT1 Antikörper (N-Term)

Produktnummer ABIN3042350

Produktdetails anti-WNT1 Antikörper

Target: WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))

Bindungsspezifität: AA 45-74, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser WNT1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Verwendungszweck: Rabbit IgG polyclonal antibody for Proto-oncogene Wnt-1(WNT1) detection. Tested with WB in Human.

Sequenz: NLLTDSKSLQ LVLEPSLQLL SRKQRRLIRQ

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Proto-oncogene Wnt-1(WNT1) detection. Tested with WB in Human.
Gene Name: wingless-type MMTV integration site family, member 1
Protein Name: Proto-oncogene Wnt-1

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Wnt1 (45-74aa NLLTDSKSLQLVLEPSLQLLSRKQRRLIRQ), identical to the related mouse and rat sequences.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Wnt1 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Referenzen für anti-WNT1 Antikörper (ABIN3042350)

Mi, Li, Zhang, Zhao, Peng, Yang, Zheng: "MicroRNA-139-5p regulates C2C12 cell myogenesis through blocking Wnt/β-catenin signaling pathway." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 93, Issue 1, pp. 8-15, (2015) (PubMed).

Dong, Duan, Han, Zhang, Wu: "Suppression of wingless-type MMTV integration site family, member 1 expression by small interfering RNA inhibits U251 glioma cell growth in vitro." in: Oncology letters, Vol. 9, Issue 1, pp. 81-85, (2014) (PubMed).

Details zu WNT1

Target: WNT1 (Wingless-Type MMTV Integration Site Family, Member 1 (WNT1))

Andere Bezeichnung: WNT1 (WNT1 Produkte)

Synonyme: Xint-1 antikoerper, Xwnt1 antikoerper, int-1 antikoerper, int1 antikoerper, wnt-1 antikoerper, wnt1-a antikoerper, Int-1 antikoerper, Wnt-1 antikoerper, sw antikoerper, swaying antikoerper, BMND16 antikoerper, INT1 antikoerper, OI15 antikoerper, Int1 antikoerper, WNT-1 antikoerper, sb:eu647 antikoerper, zgc:194464 antikoerper, zgc:194478 antikoerper, WNT1 antikoerper, Wnt family member 1 antikoerper, Wnt family member 1 L homeolog antikoerper, wingless-type MMTV integration site family, member 1 antikoerper, WNT1 antikoerper, wnt1.L antikoerper, Wnt1 antikoerper, wnt1 antikoerper

Hintergrund: Wingless-type MMIV integration site family, member 1 is a protein that in humans is encoded by the WNT1 gene. This gene is a member of the WNT gene family. The gene was assigned to human chromosome 12q13.12. The WNT gene family consists of structurally related genes that encode secreted signaling proteins. The Wnt1 protein functions in the induction of the mesencephalon and cerebellum. However, the gene mutations might not have a significant role in Joubert syndrome.

Synonyms: BMND16 antibody|INT1 antibody|OI15 antibody|oncogene Int1 antibody|Proto oncogene protein Wnt 1 antibody|Proto-oncogene Int-1 homolog antibody|Proto-oncogene Wnt-1 antibody|Wingless type MMTV integration site family member 1 antibody|wingless-type MMTV integration site family, member 1 (oncogene INT1) antibody|Wnt 1 antibody|wnt1 antibody|WNT1_HUMAN antibody

Gen-ID: 7471

UniProt: P04628

Pathways: WNT Signalweg, Dopaminergic Neurogenesis