YES1 Antikörper (N-Term)

Produktnummer ABIN3042333

Produktdetails anti-YES1 Antikörper

Target: YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))

Bindungsspezifität: AA 7-35, N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser YES1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Verwendungszweck: Rabbit IgG polyclonal antibody for Tyrosine-protein kinase Yes(YES1) detection. Tested with WB, IHC-P in Human.

Sequenz: KENKSPAIKY RPENTPEPVS TSVSHYGAE

Kreuzreaktivität (Details): No cross reactivity with other proteins.

Produktmerkmale: Rabbit IgG polyclonal antibody for Tyrosine-protein kinase Yes(YES1) detection. Tested with WB, IHC-P in Human.
Gene Name: YES proto-oncogene 1, Src family tyrosine kinase
Protein Name: Tyrosine-protein kinase Yes

Aufreinigung: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human Yes1 (7-35aa KENKSPAIKYRPENTPEPVSTSVSHYGAE), different from the related mouse sequence by six amino acids, and from the related rat sequence by seven amino acids.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, The detection limit for Yes1 is approximately 0.1 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Kommentare:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Rekonstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Konzentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Details zu YES1

Target: YES1 (V-Yes-1 Yamaguchi Sarcoma Viral Oncogene Homolog 1 (YES1))

Andere Bezeichnung: YES1 (YES1 Produkte)

Synonyme: HsT441 antikoerper, P61-YES antikoerper, Yes antikoerper, c-yes antikoerper, yes antikoerper, p61-Yes antikoerper, hst441 antikoerper, p61-yes antikoerper, YES antikoerper, c-Yes antikoerper, p60c-yes antikoerper, YES proto-oncogene 1, Src family tyrosine kinase antikoerper, YES proto-oncogene 1, Src family tyrosine kinase L homeolog antikoerper, YES1 antikoerper, yes1.L antikoerper, yes1 antikoerper, Yes1 antikoerper

Hintergrund: Proto-oncogene tyrosine-protein kinase Yes is an enzyme that in humans is encoded by the YES1 gene. This gene is the cellular homolog of the Yamaguchi sarcoma virus oncogene. The encoded protein has tyrosine kinase activity and belongs to the src family of proteins. This gene lies in close proximity to thymidylate synthase gene on chromosome 18, and a corresponding pseudogene has been found on chromosome 22. YES1 has been shown to interact with Janus kinase 2, CTNND1, RPL10 and Occludin.

Synonyms: c Yes antibody|Cellular Yes 1 protein antibody|Cellular Yes1 protein antibody|HsT441 antibody|P61 YES antibody|p61-Yes antibody|Proto oncogene tyrosine protein kinase YES antibody|Proto-oncogene c-Yes antibody|Proto-oncogene tyrosine-protein kinase Yes antibody| Tyrosine-protein kinase Yes antibody|v yes 1 Yamaguchi sarcoma viral oncogene homolog 1 antibody|Viral oncogene yes 1 homolog 1 antibody|Viral oncogene yes1 homolog 1 antibody| Yamaguchi sarcoma oncogene antibody|Yes 1 antibody|Yes antibody|YES_HUMAN antibody|YES1 antibody

Gen-ID: 7525

UniProt: P07947

Pathways: CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, Thromboxane A2 Receptor Signaling