Telefon:
+49 (0)241 95 163 153
Fax:
+49 (0)241 95 163 155
E-Mail:
orders@antikoerper-online.de

PCSK4 Antikörper (N-Term)

PCSK4 Reaktivität: Maus, Ratte WB Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN3032335
  • Target Alle PCSK4 Antikörper anzeigen
    PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))
    Bindungsspezifität
    • 15
    • 10
    • 8
    • 6
    • 2
    • 1
    • 1
    N-Term
    Reaktivität
    • 34
    • 20
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Maus, Ratte
    Wirt
    • 36
    • 1
    Kaninchen
    Klonalität
    • 37
    Polyklonal
    Konjugat
    • 13
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser PCSK4 Antikörper ist unkonjugiert
    Applikation
    • 37
    • 18
    • 13
    • 13
    • 3
    • 3
    • 1
    Western Blotting (WB)
    Aufreinigung
    Antigen affinity
    Immunogen
    An amino acid sequence from the N-terminus of mouse Proprotein convertase 4 (DPWFSKQWYMNKEIQQD) was used as the immunogen for this Proprotein Convertase 4 antibody.
    Isotyp
    IgG
    Top Product
    Discover our top product PCSK4 Primärantikörper
  • Applikationshinweise
    The stated application concentrations are suggested starting amounts. Titration of the Proprotein Convertase 4 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Buffer
    0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
    Lagerung
    -20 °C
    Informationen zur Lagerung
    After reconstitution, the Proprotein Convertase 4 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
  • Target
    PCSK4 (Proprotein Convertase Subtilisin/kexin Type 4 (PCSK4))
    Andere Bezeichnung
    Proprotein Convertase 4 (PCSK4 Produkte)
    Synonyme
    PC4 antikoerper, SPC5 antikoerper, AI647044 antikoerper, L21221 antikoerper, NEC 3 antikoerper, NEC3 antikoerper, PCSK4 antikoerper, pc4 antikoerper, spc5 antikoerper, MGC146505 antikoerper, pcsk4 antikoerper, proprotein convertase subtilisin/kexin type 4 antikoerper, proprotein convertase subtilisin/kexin type 4 L homeolog antikoerper, PCSK4 antikoerper, Pcsk4 antikoerper, pcsk4 antikoerper, pcsk4.L antikoerper
    Hintergrund
    Proprotein Convertase, Subtilisin/Kexin-Type, 4, is an enzyme that in humans is encoded by the PCSK4 gene. The gene was mapped to mouse chromosome 10, close to the adipsin locus and near the gene encoding anti-mullerian hormone. Qiu et al.(2005) found that aberrant processing of pro-IGF2 may be a cause of IUGR. PCSK4 cleaved pro-IGF2 to generate the intermediate processed form, IGF2(1-102). Mature IGF2(1-67), likely resulting from further processing by carboxypeptidases, is capable of activating invasive trophoblast cells through AKT phosphorylation. Inhibition of the protein by a PCSK4-specific inhibitor blocked pro-IGF2 processing and reduced trophoblast cell migration.
    UniProt
    P29121
Sie sind hier:
Kundenservice